Sample pretreatment on microfabricated devices

Jan Lichtenberg; Nico F. de Rooij; Elisabeth Verpoorte

doi:10.1016/S0039-9140(01)00593-8

Sample pretreatment on microfabricated devices

Jan Lichtenberg, Nico F. de Rooij, Elisabeth Verpoorte^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

163 Citations (Scopus)

Abstract

The integration of sample pretreatment into microfluidic devices represents one of the remaining hurdles towards achieving true miniaturized total analysis systems (μTAS). The challenge is made more complex by the enormous variation in samples to be analyzed. Moreover, the pretreatment technique has to be compatible with the analysis device to which it is coupled in terms of time, reagent and power consumption, as well as sample volume. This review provides a thorough overview of the developments in this field to date.

Original language	English
Pages (from-to)	233-266
Number of pages	34
Journal	Talanta
Volume	56
Issue number	2
DOIs	https://doi.org/10.1016/S0039-9140(01)00593-8
Publication status	Published - 11-Feb-2002
Externally published	Yes

Keywords

Dialysis
Filtering
Labeling
Microfabricated devices
Miniaturized total analysis systems
PCR
Preconcentration
Purification
Sample preparation
Sample pretreatment

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title = "Sample pretreatment on microfabricated devices",

abstract = "The integration of sample pretreatment into microfluidic devices represents one of the remaining hurdles towards achieving true miniaturized total analysis systems (μTAS). The challenge is made more complex by the enormous variation in samples to be analyzed. Moreover, the pretreatment technique has to be compatible with the analysis device to which it is coupled in terms of time, reagent and power consumption, as well as sample volume. This review provides a thorough overview of the developments in this field to date.",

keywords = "Dialysis, Filtering, Labeling, Microfabricated devices, Miniaturized total analysis systems, PCR, Preconcentration, Purification, Sample preparation, Sample pretreatment",

author = "Jan Lichtenberg and {de Rooij}, {Nico F.} and Elisabeth Verpoorte",

year = "2002",

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T1 - Sample pretreatment on microfabricated devices

AU - Lichtenberg, Jan

AU - de Rooij, Nico F.

AU - Verpoorte, Elisabeth

PY - 2002/2/11

Y1 - 2002/2/11

N2 - The integration of sample pretreatment into microfluidic devices represents one of the remaining hurdles towards achieving true miniaturized total analysis systems (μTAS). The challenge is made more complex by the enormous variation in samples to be analyzed. Moreover, the pretreatment technique has to be compatible with the analysis device to which it is coupled in terms of time, reagent and power consumption, as well as sample volume. This review provides a thorough overview of the developments in this field to date.

AB - The integration of sample pretreatment into microfluidic devices represents one of the remaining hurdles towards achieving true miniaturized total analysis systems (μTAS). The challenge is made more complex by the enormous variation in samples to be analyzed. Moreover, the pretreatment technique has to be compatible with the analysis device to which it is coupled in terms of time, reagent and power consumption, as well as sample volume. This review provides a thorough overview of the developments in this field to date.

KW - Dialysis

KW - Filtering

KW - Labeling

KW - Microfabricated devices

KW - Miniaturized total analysis systems

KW - PCR

KW - Preconcentration

KW - Purification

KW - Sample preparation

KW - Sample pretreatment

UR - http://www.scopus.com/inward/record.url?scp=0037060122&partnerID=8YFLogxK

U2 - 10.1016/S0039-9140(01)00593-8

DO - 10.1016/S0039-9140(01)00593-8

M3 - Review article

AN - SCOPUS:0037060122

SN - 0039-9140

VL - 56

SP - 233

EP - 266

JO - Talanta

JF - Talanta

IS - 2

ER -

Sample pretreatment on microfabricated devices

Abstract

Keywords

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