SecA-Mediated Protein Translocation through the SecYEG Channel

Amalina Ghaisani Komarudin, Arnold J M Driessen

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3 Citations (Scopus)


In bacteria, the Sec translocase mediates the translocation of proteins into and across the cytoplasmic membrane. It consists of a protein conducting channel SecYEG, the ATP-dependent motor SecA, and the accessory SecDF complex. Here we discuss the function and structure of the Sec translocase.

Original languageEnglish
Number of pages13
JournalMicrobiology Spectrum
Issue number4
Publication statusPublished - Jul-2019

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