Serum pneumoproteins in firefighters

Frans Greven*, Esmeralda Krop, Nena Burger, Huib Kerstjens, Dick Heederik

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Abstract

Serum Clara cell protein (CC16) and surfactant-associated protein A (SP-A) were measured in a cross-sectional study in 402 firefighters. For the population as a whole, no associations were detected between serum pneumoproteins and smoke exposure. SP-A levels were increased in symptomatic subjects exposed to fire smoke within 2 days before testing. SP-A levels were higher after an inhalation incident ever. CC16 was negatively associated with the number of fires fought in the last 12 months in current nonsmokers. These associations between pneumoprotein levels reiterate the importance of adequate use of self-contained breathing apparatus by firefighters.

Original languageEnglish
Pages (from-to)364-371
Number of pages8
JournalBiomarkers
Volume16
Issue number4
DOIs
Publication statusPublished - Jun-2011

Keywords

  • Bronchial hyperresponsiveness
  • Clara cell protein
  • surfactant-associated protein A
  • CLARA CELL PROTEIN
  • CHLORINATED SWIMMING POOLS
  • WASTE-WATER WORKERS
  • SMOKE EXPOSURE
  • GARBAGE COLLECTORS
  • HEALTH-HAZARDS
  • SP-A
  • CC16
  • BIOMARKER
  • ASTHMA

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