Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper

J. Bousquet; J. M. Anto; P. Demoly; H. J. Schuenemann; A. Togias; M. Akdis; C. Auffray; C. Bachert; T. Bieber; P. J. Bousquet; K. H. Carlsen; T. B. Casale; A. A. Cruz; T. Keil; K. C. Lodrup Carlsen; M. Maurer; K. Ohta; N. G. Papadopoulos; M. Roman Rodriguez; B. Samolinski; I. Agache; A. Andrianarisoa; C. S. Ang; I. Annesi-Maesano; F. Ballester; C. E. Baena-Cagnani; X. Basagana; E. D. Bateman; E. H. Bel; A. Bedbrook; B. Beghe; M. Beji; A. Ben Kheder; M. Benet; K. S. Bennoor; K. C. Bergmann; F. Berrissoul; C. Bindslev Jensen; E. R. Bleecker; S. Bonini; A. L. Boner; L. P. Boulet; C. E. Brightling; J. L. Brozek; L. Cox; M. Kerkhof; G. H. Koppelman; M. C. Nawijn; D. S. Postma; D. Y. Wang; WHO Collaborating Ctr Asthma

doi:10.1159/000332924

Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper

J. Bousquet^*, J. M. Anto, P. Demoly, H. J. Schuenemann, A. Togias, M. Akdis, C. Auffray, C. Bachert, T. Bieber, P. J. Bousquet, K. H. Carlsen, T. B. Casale, A. A. Cruz, T. Keil, K. C. Lodrup Carlsen, M. Maurer, K. Ohta, N. G. Papadopoulos, M. Roman Rodriguez, B. SamolinskiI. Agache, A. Andrianarisoa, C. S. Ang, I. Annesi-Maesano, F. Ballester, C. E. Baena-Cagnani, X. Basagana, E. D. Bateman, E. H. Bel, A. Bedbrook, B. Beghe, M. Beji, A. Ben Kheder, M. Benet, K. S. Bennoor, K. C. Bergmann, F. Berrissoul, C. Bindslev Jensen, E. R. Bleecker, S. Bonini, A. L. Boner, L. P. Boulet, C. E. Brightling, J. L. Brozek, L. Cox, M. Kerkhof, G. H. Koppelman, M. C. Nawijn, D. S. Postma, D. Y. Wang, WHO Collaborating Ctr Asthma

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies. Copyright (C) 2012 S. Karger AG, Basel

Original language	English
Pages (from-to)	216-231
Number of pages	16
Journal	International Archives of Allergy and Immunology
Volume	158
Issue number	3
DOIs	https://doi.org/10.1159/000332924
Publication status	Published - 2012

Keywords

Immunoglobulin E
Asthma
Rhinitis
Rhinosinusitis
Urticaria
Atopic dermatitis
QUALITY-OF-LIFE
ASTHMA CONTROL QUESTIONNAIRE
WORLD-HEALTH-ORGANIZATION
ATOPIC-DERMATITIS
CHRONIC RHINOSINUSITIS
NASAL POLYPOSIS
NONALLERGIC RHINITIS
TASK-FORCE
CHRONIC URTICARIA
RANDOMIZED-TRIAL

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Bousquet, J., Anto, J. M., Demoly, P., Schuenemann, H. J., Togias, A., Akdis, M., Auffray, C., Bachert, C., Bieber, T., Bousquet, P. J., Carlsen, K. H., Casale, T. B., Cruz, A. A., Keil, T., Carlsen, K. C. L., Maurer, M., Ohta, K., Papadopoulos, N. G., Rodriguez, M. R., ... WHO Collaborating Ctr Asthma (2012). Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper. International Archives of Allergy and Immunology, 158(3), 216-231. https://doi.org/10.1159/000332924

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title = "Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper",

abstract = "Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies. Copyright (C) 2012 S. Karger AG, Basel",

keywords = "Immunoglobulin E, Asthma, Rhinitis, Rhinosinusitis, Urticaria, Atopic dermatitis, QUALITY-OF-LIFE, ASTHMA CONTROL QUESTIONNAIRE, WORLD-HEALTH-ORGANIZATION, ATOPIC-DERMATITIS, CHRONIC RHINOSINUSITIS, NASAL POLYPOSIS, NONALLERGIC RHINITIS, TASK-FORCE, CHRONIC URTICARIA, RANDOMIZED-TRIAL",

author = "J. Bousquet and Anto, {J. M.} and P. Demoly and Schuenemann, {H. J.} and A. Togias and M. Akdis and C. Auffray and C. Bachert and T. Bieber and Bousquet, {P. J.} and Carlsen, {K. H.} and Casale, {T. B.} and Cruz, {A. A.} and T. Keil and Carlsen, {K. C. Lodrup} and M. Maurer and K. Ohta and Papadopoulos, {N. G.} and Rodriguez, {M. Roman} and B. Samolinski and I. Agache and A. Andrianarisoa and Ang, {C. S.} and I. Annesi-Maesano and F. Ballester and Baena-Cagnani, {C. E.} and X. Basagana and Bateman, {E. D.} and Bel, {E. H.} and A. Bedbrook and B. Beghe and M. Beji and {Ben Kheder}, A. and M. Benet and Bennoor, {K. S.} and Bergmann, {K. C.} and F. Berrissoul and Jensen, {C. Bindslev} and Bleecker, {E. R.} and S. Bonini and Boner, {A. L.} and Boulet, {L. P.} and Brightling, {C. E.} and Brozek, {J. L.} and L. Cox and M. Kerkhof and Koppelman, {G. H.} and Nawijn, {M. C.} and Postma, {D. S.} and Wang, {D. Y.} and {WHO Collaborating Ctr Asthma}",

year = "2012",

doi = "10.1159/000332924",

language = "English",

volume = "158",

pages = "216--231",

journal = "International Archives of Allergy and Immunology",

issn = "1018-2438",

publisher = "KARGER",

number = "3",

}

Bousquet, J, Anto, JM, Demoly, P, Schuenemann, HJ, Togias, A, Akdis, M, Auffray, C, Bachert, C, Bieber, T, Bousquet, PJ, Carlsen, KH, Casale, TB, Cruz, AA, Keil, T, Carlsen, KCL, Maurer, M, Ohta, K, Papadopoulos, NG, Rodriguez, MR, Samolinski, B, Agache, I, Andrianarisoa, A, Ang, CS, Annesi-Maesano, I, Ballester, F, Baena-Cagnani, CE, Basagana, X, Bateman, ED, Bel, EH, Bedbrook, A, Beghe, B, Beji, M, Ben Kheder, A, Benet, M, Bennoor, KS, Bergmann, KC, Berrissoul, F, Jensen, CB, Bleecker, ER, Bonini, S, Boner, AL, Boulet, LP, Brightling, CE, Brozek, JL, Cox, L, Kerkhof, M, Koppelman, GH , Nawijn, MC, Postma, DS, Wang, DY & WHO Collaborating Ctr Asthma 2012, 'Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper', International Archives of Allergy and Immunology, vol. 158, no. 3, pp. 216-231. https://doi.org/10.1159/000332924

TY - JOUR

T1 - Severe Chronic Allergic (and Related) Diseases

T2 - A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper

AU - Bousquet, J.

AU - Anto, J. M.

AU - Demoly, P.

AU - Schuenemann, H. J.

AU - Togias, A.

AU - Akdis, M.

AU - Auffray, C.

AU - Bachert, C.

AU - Bieber, T.

AU - Bousquet, P. J.

AU - Carlsen, K. H.

AU - Casale, T. B.

AU - Cruz, A. A.

AU - Keil, T.

AU - Carlsen, K. C. Lodrup

AU - Maurer, M.

AU - Ohta, K.

AU - Papadopoulos, N. G.

AU - Rodriguez, M. Roman

AU - Samolinski, B.

AU - Agache, I.

AU - Andrianarisoa, A.

AU - Ang, C. S.

AU - Annesi-Maesano, I.

AU - Ballester, F.

AU - Baena-Cagnani, C. E.

AU - Basagana, X.

AU - Bateman, E. D.

AU - Bel, E. H.

AU - Bedbrook, A.

AU - Beghe, B.

AU - Beji, M.

AU - Ben Kheder, A.

AU - Benet, M.

AU - Bennoor, K. S.

AU - Bergmann, K. C.

AU - Berrissoul, F.

AU - Jensen, C. Bindslev

AU - Bleecker, E. R.

AU - Bonini, S.

AU - Boner, A. L.

AU - Boulet, L. P.

AU - Brightling, C. E.

AU - Brozek, J. L.

AU - Cox, L.

AU - Kerkhof, M.

AU - Koppelman, G. H.

AU - Nawijn, M. C.

AU - Postma, D. S.

AU - Wang, D. Y.

AU - WHO Collaborating Ctr Asthma

PY - 2012

Y1 - 2012

N2 - Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies. Copyright (C) 2012 S. Karger AG, Basel

AB - Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies. Copyright (C) 2012 S. Karger AG, Basel

KW - Immunoglobulin E

KW - Asthma

KW - Rhinitis

KW - Rhinosinusitis

KW - Urticaria

KW - Atopic dermatitis

KW - QUALITY-OF-LIFE

KW - ASTHMA CONTROL QUESTIONNAIRE

KW - WORLD-HEALTH-ORGANIZATION

KW - ATOPIC-DERMATITIS

KW - CHRONIC RHINOSINUSITIS

KW - NASAL POLYPOSIS

KW - NONALLERGIC RHINITIS

KW - TASK-FORCE

KW - CHRONIC URTICARIA

KW - RANDOMIZED-TRIAL

U2 - 10.1159/000332924

DO - 10.1159/000332924

M3 - Article

SN - 1018-2438

VL - 158

SP - 216

EP - 231

JO - International Archives of Allergy and Immunology

JF - International Archives of Allergy and Immunology

IS - 3

ER -

Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper

Abstract

Keywords

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