BACKGROUND. The goals of sentinel lymph node biopsy (SLNB) are to improve axillary staging and reduce unnecessary axillary lymph node dissections (ALND), thereby reducing treatment-related upper-limb morbidity. In the current prospective study, short-term upper-limb morbidity was assessed after SLNB and/or ALND.
METHODS. The study comprised 204 patients with Stage I/II breast carcinoma. Mean patient age was 55.6 years (standard deviation, 11.6). Sixty-six patients (32%) underwent SLNB only, and 138 (68%) underwent a Level I-II ALND. Assessment (preoperative [t0] and 6 weeks postoperative [t1]) included evaluation of shoulder range of motion, muscle strength, grip strength, pain, upper/forearm circumference, shoulder disability, and activities of daily life (ADL).
RESULTS. Considerable treatment-related upper-limb morbidity was observed. Significant (P <0.001) changes were found for pain, range of motion in forward flexion, abduction and abduction/external rotation, strength of shoulder abductors and elbow flexors, and in perceived disability in ADL. However, no significant difference in change of upper-limb function and ADL was found between the SLNB and ALND groups.
CONCLUSIONS. Significant short-term treatment-related upper-limb morbidity exists after SLNB or ALND. There is no significant difference in short-term treatment-related morbidity between SLNB and ALND.
|Number of pages||7|
|Publication status||Published - 15-Aug-2003|
|Event||55th Annual Cancer Symposium of the Society-of-Surgical-Oncology - |
Duration: 14-Mar-2002 → 17-Mar-2002
- breast carcinoma
- sentinel lymph node
- activities of daily life
- ARM MORBIDITY
- PSYCHOLOGICAL MORBIDITY
- CANCER PATIENTS