TY - JOUR
T1 - Six-year course over time and predictors of suicidal ideation in depressed older patients
AU - Zuidersma, Marij
AU - de Vries, Ymkje Anna
AU - Bogers, Ista C.H.M.
AU - Rhebergen, Didi
AU - Oude Voshaar, Richard C.
N1 - Publisher Copyright:
© 2024
PY - 2025/2/1
Y1 - 2025/2/1
N2 - Background: It is important to know predictors of long-term course over time of suicidal thoughts and ideation in depressed older persons.Methods: In this study, 378 depressed older persons were interviewed at baseline, and after 2 and 6 years to evaluate the presence of depressive disorder. The Inventory of Depressive Symptomatology (IDS) was administered every 6 months for 6 years. Latent Class Growth Analysis was performed on the IDS item on suicidal ideation to identify subgroups with different trajectories.Results: Five subgroups with suicidal ideation trajectories were identified: 1) severe, transient (10.9 %), 2) severe, persisting (8.0 %), 3) mild, but increasing (14.9 %), 4) moderate, persisting (35.6 %), and 5) no thoughts (30.6 %). Mixed model analysis showed that trajectories were related to 6-year course of depressive symptoms. Yet, suicidal ideation or thoughts of loss of meaning of life were still present in 22.7 % and 17.4 % of those who remitted after 2 and 6 years. Independent of baseline depressive symptom severity, loneliness, childhood trauma, history of suicidal ideation or attempt, openness to experience, earlier age of depression onset, anxiety symptom severity and worse mastery predicted worse trajectories.Limitations: 47 % dropped out at 6-years follow-up, we did not distinguish between thoughts of death and suicide, we did not assess death by suicide.Conclusions: Although trajectories of suicidal ideation and thoughts of loss of meaning of life were strongly related to the course of depression severity, they also appear after remission. Clinicians should be vigilant for suicidal ideation or death wish, even after remission of depression.
AB - Background: It is important to know predictors of long-term course over time of suicidal thoughts and ideation in depressed older persons.Methods: In this study, 378 depressed older persons were interviewed at baseline, and after 2 and 6 years to evaluate the presence of depressive disorder. The Inventory of Depressive Symptomatology (IDS) was administered every 6 months for 6 years. Latent Class Growth Analysis was performed on the IDS item on suicidal ideation to identify subgroups with different trajectories.Results: Five subgroups with suicidal ideation trajectories were identified: 1) severe, transient (10.9 %), 2) severe, persisting (8.0 %), 3) mild, but increasing (14.9 %), 4) moderate, persisting (35.6 %), and 5) no thoughts (30.6 %). Mixed model analysis showed that trajectories were related to 6-year course of depressive symptoms. Yet, suicidal ideation or thoughts of loss of meaning of life were still present in 22.7 % and 17.4 % of those who remitted after 2 and 6 years. Independent of baseline depressive symptom severity, loneliness, childhood trauma, history of suicidal ideation or attempt, openness to experience, earlier age of depression onset, anxiety symptom severity and worse mastery predicted worse trajectories.Limitations: 47 % dropped out at 6-years follow-up, we did not distinguish between thoughts of death and suicide, we did not assess death by suicide.Conclusions: Although trajectories of suicidal ideation and thoughts of loss of meaning of life were strongly related to the course of depression severity, they also appear after remission. Clinicians should be vigilant for suicidal ideation or death wish, even after remission of depression.
KW - Depression
KW - Latent class growth analysis
KW - Old age psychiatry
KW - Thoughts of death
KW - Trajectories
UR - http://www.scopus.com/inward/record.url?scp=85208146274&partnerID=8YFLogxK
U2 - 10.1016/j.jad.2024.10.097
DO - 10.1016/j.jad.2024.10.097
M3 - Article
C2 - 39481688
AN - SCOPUS:85208146274
SN - 0165-0327
VL - 370
SP - 90
EP - 99
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
ER -