Skin autofluorescence, a non-invasive biomarker for advanced glycation end products, is not related to the number of pregnancies

Robert P. Van Waateringe; Laura Truyens; Paul P. Van Den Berg; Helen L. Lutgers; Bruce H. R. Wolffenbuttel

doi:10.1111/1753-0407.12782

Skin autofluorescence, a non-invasive biomarker for advanced glycation end products, is not related to the number of pregnancies

Robert P. Van Waateringe, Laura Truyens, Paul P. Van Den Berg, Helen L. Lutgers, Bruce H. R. Wolffenbuttel^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

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Abstract

Highlights

Skin autofluorescence (SAF) assesses subcutaneous accumulation of advanced glycation end products and has been shown to predict future cardiovascular disease and diabetes.

A higher number of pregnancies was significantly associated with higher SAF, even after correction for relevant confounders like waist circumference, creatinine clearance, and diabetes status, but not after correction for age.

Women with the highest SAF Z-score had a more unfavorable risk factor profile, with higher body mass index and waist circumference, higher blood pressure, lower high-density lipoprotein cholesterol, and higher triglyceride levels.

Original language	English
Pages (from-to)	899-901
Number of pages	3
Journal	Journal of diabetes
Volume	10
Issue number	11
DOIs	https://doi.org/10.1111/1753-0407.12782
Publication status	Published - Nov-2018

Keywords

aging
diabetes
epidemiology
pregnancy
skin autofluorescence
PREECLAMPTIC WOMEN
OXIDATIVE STRESS
ACCUMULATION
ASSOCIATION
MARKER

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Skin autofluorescence, a non‐invasive biomarker for advanced glycation end products, is not related to the number of pregnanciesFinal publisher's version, 199 KBLicence: CC BY

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Cite this

@article{0235127110334a89b969b989698f8b7c,

title = "Skin autofluorescence, a non-invasive biomarker for advanced glycation end products, is not related to the number of pregnancies",

abstract = "HighlightsSkin autofluorescence (SAF) assesses subcutaneous accumulation of advanced glycation end products and has been shown to predict future cardiovascular disease and diabetes.A higher number of pregnancies was significantly associated with higher SAF, even after correction for relevant confounders like waist circumference, creatinine clearance, and diabetes status, but not after correction for age.Women with the highest SAF Z-score had a more unfavorable risk factor profile, with higher body mass index and waist circumference, higher blood pressure, lower high-density lipoprotein cholesterol, and higher triglyceride levels.",

keywords = "aging, diabetes, epidemiology, pregnancy, skin autofluorescence, PREECLAMPTIC WOMEN, OXIDATIVE STRESS, ACCUMULATION, ASSOCIATION, MARKER",

author = "{Van Waateringe}, {Robert P.} and Laura Truyens and {Van Den Berg}, {Paul P.} and Lutgers, {Helen L.} and Wolffenbuttel, {Bruce H. R.}",

year = "2018",

month = nov,

doi = "10.1111/1753-0407.12782",

language = "English",

volume = "10",

pages = "899--901",

journal = "Journal of diabetes",

issn = "1753-0393",

publisher = "Wiley",

number = "11",

}

TY - JOUR

T1 - Skin autofluorescence, a non-invasive biomarker for advanced glycation end products, is not related to the number of pregnancies

AU - Van Waateringe, Robert P.

AU - Truyens, Laura

AU - Van Den Berg, Paul P.

AU - Lutgers, Helen L.

AU - Wolffenbuttel, Bruce H. R.

PY - 2018/11

Y1 - 2018/11

N2 - HighlightsSkin autofluorescence (SAF) assesses subcutaneous accumulation of advanced glycation end products and has been shown to predict future cardiovascular disease and diabetes.A higher number of pregnancies was significantly associated with higher SAF, even after correction for relevant confounders like waist circumference, creatinine clearance, and diabetes status, but not after correction for age.Women with the highest SAF Z-score had a more unfavorable risk factor profile, with higher body mass index and waist circumference, higher blood pressure, lower high-density lipoprotein cholesterol, and higher triglyceride levels.

AB - HighlightsSkin autofluorescence (SAF) assesses subcutaneous accumulation of advanced glycation end products and has been shown to predict future cardiovascular disease and diabetes.A higher number of pregnancies was significantly associated with higher SAF, even after correction for relevant confounders like waist circumference, creatinine clearance, and diabetes status, but not after correction for age.Women with the highest SAF Z-score had a more unfavorable risk factor profile, with higher body mass index and waist circumference, higher blood pressure, lower high-density lipoprotein cholesterol, and higher triglyceride levels.

KW - aging

KW - diabetes

KW - epidemiology

KW - pregnancy

KW - skin autofluorescence

KW - PREECLAMPTIC WOMEN

KW - OXIDATIVE STRESS

KW - ACCUMULATION

KW - ASSOCIATION

KW - MARKER

U2 - 10.1111/1753-0407.12782

DO - 10.1111/1753-0407.12782

M3 - Comment/Letter to the editor

SN - 1753-0393

VL - 10

SP - 899

EP - 901

JO - Journal of diabetes

JF - Journal of diabetes

IS - 11

ER -