Solubilization of lipids and lipid phases by the styrene-maleic acid copolymer

Juan J. Dominguez Pardo, Jonas M. Dörr, Aditya Iyer, Ruud C. Cox, Stefan Scheidelaar, Martijn C. Koorengevel, Vinod Subramaniam, J. Antoinette Killian

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Abstract

any solubilization preference of SMA is not due to proper-ties of individual lipids but rather due to properties of the membrane or membrane domains in which these lipids reside and (3) exploiting SMA resistance rather than deter-gent resistance may be an attractive approach for the isola-tion of ordered domains from biological membranes.
Original languageEnglish
Pages (from-to)91-101
Number of pages11
JournalBiophysics of Structure and Mechanism
Volume46 (2017)
DOIs
Publication statusPublished - 4-Nov-2016
Externally publishedYes

Keywords

  • Lipid rafts
  • Lipid???protein interactions
  • Nanodiscs
  • SMA-resistant membrane (SRM)
  • SMALP
  • Styrene???maleic acid

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