Sorting the trash: Micronucleophagy gets selective

Pauline Verlhac, Fulvio Reggiori

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Abstract

During micronucleophagy, the nucleolus is targeted by autophagic degradation, but although nucleolar proteins are recycled, ribosomal DNA is spared. Mostofa et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201706164) reveal that the separation of these two nucleolar components is mediated by the CLIP and cohibin complexes and is vital for cell survival during starvation.

Original languageEnglish
Pages (from-to)2605-2607
Number of pages3
JournalThe Journal of Cell Biology
Volume217
Issue number8
DOIs
Publication statusPublished - Aug-2018

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