Spatial mapping of Alzheimer’s disease across genetic subtypes: Spatial transcriptomics

Alexi Nott; Inge R. Holtman

doi:10.1038/s41588-024-01895-4

Spatial mapping of Alzheimer’s disease across genetic subtypes: Spatial transcriptomics

Alexi Nott^*
, Inge R. Holtman^*

^*Corresponding author for this work

Senescence, Stem Cells, and Inflammation (SSI)

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

1 Citation (Scopus)

97 Downloads (Pure)

Abstract

Alzheimer’s disease is a complex, heterogeneous disorder with multiple genetic subtypes. Spatial and single-cell gene expression analyses of these subtypes have provided new insights into general and subtype-specific cellular and molecular mechanisms of Alzheimer’s disease.

Original language	English
Article number	4710
Pages (from-to)	2592-2593
Number of pages	2
Journal	Nature genetics
Volume	56
Issue number	12
DOIs	https://doi.org/10.1038/s41588-024-01895-4
Publication status	Published - Dec-2024

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Spatial mapping of Alzheimer’s disease across genetic subtypesFinal publisher's version, 1.23 MBLicence: Taverne

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title = "Spatial mapping of Alzheimer{\textquoteright}s disease across genetic subtypes: Spatial transcriptomics",

abstract = "Alzheimer{\textquoteright}s disease is a complex, heterogeneous disorder with multiple genetic subtypes. Spatial and single-cell gene expression analyses of these subtypes have provided new insights into general and subtype-specific cellular and molecular mechanisms of Alzheimer{\textquoteright}s disease.",

author = "Alexi Nott and Holtman, \{Inge R.\}",

note = "Publisher Copyright: {\textcopyright} Springer Nature America, Inc. 2024.",

year = "2024",

month = dec,

doi = "10.1038/s41588-024-01895-4",

language = "English",

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T1 - Spatial mapping of Alzheimer’s disease across genetic subtypes

T2 - Spatial transcriptomics

AU - Nott, Alexi

AU - Holtman, Inge R.

N1 - Publisher Copyright: © Springer Nature America, Inc. 2024.

PY - 2024/12

Y1 - 2024/12

N2 - Alzheimer’s disease is a complex, heterogeneous disorder with multiple genetic subtypes. Spatial and single-cell gene expression analyses of these subtypes have provided new insights into general and subtype-specific cellular and molecular mechanisms of Alzheimer’s disease.

AB - Alzheimer’s disease is a complex, heterogeneous disorder with multiple genetic subtypes. Spatial and single-cell gene expression analyses of these subtypes have provided new insights into general and subtype-specific cellular and molecular mechanisms of Alzheimer’s disease.

UR - https://www.scopus.com/pages/publications/85210157283

U2 - 10.1038/s41588-024-01895-4

DO - 10.1038/s41588-024-01895-4

M3 - Comment/Letter to the editor

C2 - 39587362

AN - SCOPUS:85210157283

SN - 1061-4036

VL - 56

SP - 2592

EP - 2593

JO - Nature genetics

JF - Nature genetics

IS - 12

M1 - 4710

ER -

Spatial mapping of Alzheimer’s disease across genetic subtypes: Spatial transcriptomics

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