Stereolithographic fabrication and characterization of immobilized enzyme reactors for in vitro digestions

Research output: Contribution to conferenceAbstractAcademic

Abstract

Enzymatic digestion is a key process in the gastrointestinal tract that we recreated in an earlier miniaturized system. In order to avoid the need to continuously supply digestive enzymes, this work studied the immobilization of digestive enzymes in a microsystem. Flow-through reactors were produced by stereolithography and the digestive enzyme, alpha-amylase, was immobilized onto the channel walls. The activity of immobilized alpha-amylase was determined by digestion of starch, with potential applications in organs-on-a-chip or other enzymatic conversions.
Original languageEnglish
Pages1169
Number of pages2
Publication statusPublished - 13-Oct-2021
Event25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2021): MicroTAS 2021 - Palm Springs, United States
Duration: 10-Oct-202114-Oct-2021
Conference number: 25
http://microtas2021.org

Conference

Conference25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2021)
Abbreviated titleµTAS 2021
Country/TerritoryUnited States
CityPalm Springs
Period10/10/202114/10/2021
Internet address

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