Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases

K. de With; F. Allerberger; S. Amann; P. Apfalter; H. -R. Brodt; T. Eckmanns; M. Fellhauer; H. K. Geiss; O. Janata; R. Krause; S. Lemmen; E. Meyer; H. Mittermayer; U. Porsche; E. Presterl; S. Reuter; B. Sinha; R. Strauss; A. Wechsler-Foerdoes; C. Wenisch; W. V. Kern

doi:10.1007/s15010-016-0885-z

Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases

K. de With^*
, F. Allerberger
, S. Amann
, P. Apfalter
, H. -R. Brodt
, T. Eckmanns
, M. Fellhauer
, H. K. Geiss
, O. Janata
, R. Krause
, S. Lemmen
, E. Meyer
, H. Mittermayer
, U. Porsche
, E. Presterl
, S. Reuter
, B. Sinha
, R. Strauss
, A. Wechsler-Foerdoes
, C. Wenisch

W. V. Kern

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

174 Citations (Scopus)

636 Downloads (Pure)

Abstract

In the time of increasing resistance and paucity of new drug development there is a growing need for strategies to enhance rational use of antibiotics in German and Austrian hospitals. An evidence-based guideline on recommendations for implementation of antibiotic stewardship (ABS) programmes was developed by the German Society for Infectious Diseases in association with the following societies, associations and institutions: German Society of Hospital Pharmacists, German Society for Hygiene and Microbiology, Paul Ehrlich Society for Chemotherapy, The Austrian Association of Hospital Pharmacists, Austrian Society for Infectious Diseases and Tropical Medicine, Austrian Society for Antimicrobial Chemotherapy, Robert Koch Institute.

A structured literature research was performed in the databases EMBASE, BIOSIS, MEDLINE and The Cochrane Library from January 2006 to November 2010 with an update to April 2012 (MEDLINE and The Cochrane Library). The grading of recommendations in relation to their evidence is according to the AWMF Guidance Manual and Rules for Guideline Development.

The guideline provides the grounds for rational use of antibiotics in hospital to counteract antimicrobial resistance and to improve the quality of care of patients with infections by maximising clinical outcomes while minimising toxicity. Requirements for a successful implementation of ABS programmes as well as core and supplemental ABS strategies are outlined. The German version of the guideline was published by the German Association of the Scientific Medical Societies (AWMF) in December 2013.

Original language	English
Pages (from-to)	395-439
Number of pages	45
Journal	Infection
Volume	44
Issue number	3
Early online date	11-Apr-2016
DOIs	https://doi.org/10.1007/s15010-016-0885-z
Publication status	Published - Jun-2016

Keywords

Antibiotic stewardship
ABS
Guideline
Antimicrobial resistance
Quality of care
Rational use
COMMUNITY-ACQUIRED PNEUMONIA
INTENSIVE-CARE-UNIT
VENTILATOR-ASSOCIATED PNEUMONIA
RESISTANT STAPHYLOCOCCUS-AUREUS
RANDOMIZED CONTROLLED-TRIAL
ANTIMICROBIAL STEWARDSHIP PROGRAMS
TIME-SERIES ANALYSIS
CLOSTRIDIUM-DIFFICILE INFECTION
CRITICALLY-ILL PATIENTS
CLINICAL DECISION-SUPPORT

Access to Document

10.1007/s15010-016-0885-z

Strategies to enhance rational use of antibiotics in hospitalFinal publisher's version, 1.11 MBLicence: CC BY

Handle.net

Persistent link

Cite this

de With, K., Allerberger, F., Amann, S., Apfalter, P., Brodt, H. .-R., Eckmanns, T., Fellhauer, M., Geiss, H. K., Janata, O., Krause, R., Lemmen, S., Meyer, E., Mittermayer, H., Porsche, U., Presterl, E., Reuter, S., Sinha, B., Strauss, R., Wechsler-Foerdoes, A., ... Kern, W. V. (2016). Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases. Infection, 44(3), 395-439. https://doi.org/10.1007/s15010-016-0885-z

@article{f800cb6665ef4f3892b4ad3259a983c5,

title = "Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases",

abstract = "In the time of increasing resistance and paucity of new drug development there is a growing need for strategies to enhance rational use of antibiotics in German and Austrian hospitals. An evidence-based guideline on recommendations for implementation of antibiotic stewardship (ABS) programmes was developed by the German Society for Infectious Diseases in association with the following societies, associations and institutions: German Society of Hospital Pharmacists, German Society for Hygiene and Microbiology, Paul Ehrlich Society for Chemotherapy, The Austrian Association of Hospital Pharmacists, Austrian Society for Infectious Diseases and Tropical Medicine, Austrian Society for Antimicrobial Chemotherapy, Robert Koch Institute.A structured literature research was performed in the databases EMBASE, BIOSIS, MEDLINE and The Cochrane Library from January 2006 to November 2010 with an update to April 2012 (MEDLINE and The Cochrane Library). The grading of recommendations in relation to their evidence is according to the AWMF Guidance Manual and Rules for Guideline Development.The guideline provides the grounds for rational use of antibiotics in hospital to counteract antimicrobial resistance and to improve the quality of care of patients with infections by maximising clinical outcomes while minimising toxicity. Requirements for a successful implementation of ABS programmes as well as core and supplemental ABS strategies are outlined. The German version of the guideline was published by the German Association of the Scientific Medical Societies (AWMF) in December 2013.",

keywords = "Antibiotic stewardship, ABS, Guideline, Antimicrobial resistance, Quality of care, Rational use, COMMUNITY-ACQUIRED PNEUMONIA, INTENSIVE-CARE-UNIT, VENTILATOR-ASSOCIATED PNEUMONIA, RESISTANT STAPHYLOCOCCUS-AUREUS, RANDOMIZED CONTROLLED-TRIAL, ANTIMICROBIAL STEWARDSHIP PROGRAMS, TIME-SERIES ANALYSIS, CLOSTRIDIUM-DIFFICILE INFECTION, CRITICALLY-ILL PATIENTS, CLINICAL DECISION-SUPPORT",

author = "\{de With\}, K. and F. Allerberger and S. Amann and P. Apfalter and Brodt, \{H. -R.\} and T. Eckmanns and M. Fellhauer and Geiss, \{H. K.\} and O. Janata and R. Krause and S. Lemmen and E. Meyer and H. Mittermayer and U. Porsche and E. Presterl and S. Reuter and B. Sinha and R. Strauss and A. Wechsler-Foerdoes and C. Wenisch and Kern, \{W. V.\}",

year = "2016",

month = jun,

doi = "10.1007/s15010-016-0885-z",

language = "English",

volume = "44",

pages = "395--439",

journal = "Infection",

issn = "0300-8126",

publisher = "Urban und Vogel GmbH",

number = "3",

}

de With, K, Allerberger, F, Amann, S, Apfalter, P, Brodt, H-R, Eckmanns, T, Fellhauer, M, Geiss, HK, Janata, O, Krause, R, Lemmen, S, Meyer, E, Mittermayer, H, Porsche, U, Presterl, E, Reuter, S, Sinha, B, Strauss, R, Wechsler-Foerdoes, A, Wenisch, C & Kern, WV 2016, 'Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases', Infection, vol. 44, no. 3, pp. 395-439. https://doi.org/10.1007/s15010-016-0885-z

TY - JOUR

T1 - Strategies to enhance rational use of antibiotics in hospital

T2 - a guideline by the German Society for Infectious Diseases

AU - de With, K.

AU - Allerberger, F.

AU - Amann, S.

AU - Apfalter, P.

AU - Brodt, H. -R.

AU - Eckmanns, T.

AU - Fellhauer, M.

AU - Geiss, H. K.

AU - Janata, O.

AU - Krause, R.

AU - Lemmen, S.

AU - Meyer, E.

AU - Mittermayer, H.

AU - Porsche, U.

AU - Presterl, E.

AU - Reuter, S.

AU - Sinha, B.

AU - Strauss, R.

AU - Wechsler-Foerdoes, A.

AU - Wenisch, C.

AU - Kern, W. V.

PY - 2016/6

Y1 - 2016/6

N2 - In the time of increasing resistance and paucity of new drug development there is a growing need for strategies to enhance rational use of antibiotics in German and Austrian hospitals. An evidence-based guideline on recommendations for implementation of antibiotic stewardship (ABS) programmes was developed by the German Society for Infectious Diseases in association with the following societies, associations and institutions: German Society of Hospital Pharmacists, German Society for Hygiene and Microbiology, Paul Ehrlich Society for Chemotherapy, The Austrian Association of Hospital Pharmacists, Austrian Society for Infectious Diseases and Tropical Medicine, Austrian Society for Antimicrobial Chemotherapy, Robert Koch Institute.A structured literature research was performed in the databases EMBASE, BIOSIS, MEDLINE and The Cochrane Library from January 2006 to November 2010 with an update to April 2012 (MEDLINE and The Cochrane Library). The grading of recommendations in relation to their evidence is according to the AWMF Guidance Manual and Rules for Guideline Development.The guideline provides the grounds for rational use of antibiotics in hospital to counteract antimicrobial resistance and to improve the quality of care of patients with infections by maximising clinical outcomes while minimising toxicity. Requirements for a successful implementation of ABS programmes as well as core and supplemental ABS strategies are outlined. The German version of the guideline was published by the German Association of the Scientific Medical Societies (AWMF) in December 2013.

AB - In the time of increasing resistance and paucity of new drug development there is a growing need for strategies to enhance rational use of antibiotics in German and Austrian hospitals. An evidence-based guideline on recommendations for implementation of antibiotic stewardship (ABS) programmes was developed by the German Society for Infectious Diseases in association with the following societies, associations and institutions: German Society of Hospital Pharmacists, German Society for Hygiene and Microbiology, Paul Ehrlich Society for Chemotherapy, The Austrian Association of Hospital Pharmacists, Austrian Society for Infectious Diseases and Tropical Medicine, Austrian Society for Antimicrobial Chemotherapy, Robert Koch Institute.A structured literature research was performed in the databases EMBASE, BIOSIS, MEDLINE and The Cochrane Library from January 2006 to November 2010 with an update to April 2012 (MEDLINE and The Cochrane Library). The grading of recommendations in relation to their evidence is according to the AWMF Guidance Manual and Rules for Guideline Development.The guideline provides the grounds for rational use of antibiotics in hospital to counteract antimicrobial resistance and to improve the quality of care of patients with infections by maximising clinical outcomes while minimising toxicity. Requirements for a successful implementation of ABS programmes as well as core and supplemental ABS strategies are outlined. The German version of the guideline was published by the German Association of the Scientific Medical Societies (AWMF) in December 2013.

KW - Antibiotic stewardship

KW - ABS

KW - Guideline

KW - Antimicrobial resistance

KW - Quality of care

KW - Rational use

KW - COMMUNITY-ACQUIRED PNEUMONIA

KW - INTENSIVE-CARE-UNIT

KW - VENTILATOR-ASSOCIATED PNEUMONIA

KW - RESISTANT STAPHYLOCOCCUS-AUREUS

KW - RANDOMIZED CONTROLLED-TRIAL

KW - ANTIMICROBIAL STEWARDSHIP PROGRAMS

KW - TIME-SERIES ANALYSIS

KW - CLOSTRIDIUM-DIFFICILE INFECTION

KW - CRITICALLY-ILL PATIENTS

KW - CLINICAL DECISION-SUPPORT

U2 - 10.1007/s15010-016-0885-z

DO - 10.1007/s15010-016-0885-z

M3 - Article

C2 - 27066980

SN - 0300-8126

VL - 44

SP - 395

EP - 439

JO - Infection

JF - Infection

IS - 3

ER -

Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases

Abstract

Keywords

Access to Document

Handle.net

Fingerprint

Cite this