Structural and functional characterisation of a lytic transglycosylase and two ω-transaminases

Eswarreddy Reddem

Research output: ThesisThesis fully internal (DIV)

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This thesis describes the determination and analysis of 3D-structures of enzymes from two different enzyme classes, the lytic transglycosylase MltF from Pseudomonas aeruginosa and two ω-transaminases, an (R)-selective transaminase from an Arthrobacter species and an (S)-selective transaminase from a Pseudomonas species. Lytic transglycosylases may present new targets for the development of broad-spectrum antibiotics, while the transaminases are of biotechnological importance.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • University of Groningen
  • Dijkstra, Bauke W., Supervisor, External person
  • Thunnissen, Andy, Co-supervisor
Award date22-Dec-2015
Place of Publication[Groningen]
Print ISBNs978-90-367-8503-7
Electronic ISBNs978-90-367-8502-0
Publication statusPublished - 2015

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