Successful Kidney and Lung Transplantation From a Deceased Donor With Blunt Abdominal Trauma and Intestinal Perforation

Tim C. van Smaalen*, Christina Krikke, Jan Willem Haveman, L. W. Ernest van Heurn

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

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    Abstract

    The number of organ donors is limited by many contraindications for donation and poor quality of potential organ donors. Abdominal infection is a generally accepted contraindication for donation of abdominal organs. We present a 43-year-old man with lethal brain injury, blunt abdominal trauma, and intestinal perforation. After withdrawal of life-sustaining treatment and circulatory arrest, a minilaparotomy confirmed abdominal contamination with intestinal content. After closure of the abdomen, organs were preserved with in situ preservation with an aortic cannula inserted via the femoral artery. Thereafter, the kidneys were procured via bilateral lumbotomy to reduce the risk of direct bacterial contamination; lungs were retrieved following a standard practice. There was no bacterial or fungal growth in the machine preservation fluid of both kidneys. All organs were successfully transplanted, without postoperative infection, and functioned well after 6 months. We hereby show that direct contamination of organs can be avoided with the use of in situ preservation and retroperitoneal procurement. Intestinal perforation is not an absolute contraindication for donation, although the risk of bacterial or fungal transmission has to be evaluated per case.

    Original languageEnglish
    Article number55
    Number of pages4
    JournalTransplantation direct
    Volume2
    Issue number1
    DOIs
    Publication statusPublished - Jan-2016

    Keywords

    • SOLID-ORGAN TRANSPLANTATION
    • MULTIDETECTOR CT
    • CARDIAC DEATH
    • RENAL-TRANSPLANTATION
    • FUNGAL-INFECTIONS
    • PRESERVATION
    • GUIDELINES
    • RECIPIENTS
    • CONTAMINATION
    • MANAGEMENT

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