Sudden Cardiac Death: Epidemiology, Circadian Variation, and Triggers

Karim D. Mahmoud; Bart J. G. L. de Smet; Felix Zijlstra; Charanjit S. Rihal; David R. Holmes

doi:10.1016/j.cpcardiol.2011.01.002

Sudden Cardiac Death: Epidemiology, Circadian Variation, and Triggers

Karim D. Mahmoud^*, Bart J. G. L. de Smet, Felix Zijlstra, Charanjit S. Rihal, David R. Holmes

^*Corresponding author for this work

Faculty of Medical Sciences/UMCG

Research output: Contribution to journal › Review article › peer-review

14 Citations (Scopus)

Abstract

Sudden cardiac death (SCD) remains a major health issue accounting for over 5% of annual mortality in the Western world. There are several causes of SCD, most commonly, coronary artery disease. Although identifying the prodrome of SCD has attracted considerable interest, a large proportion of patients die before any medical contact is established. SCD onset seems to follow a circadian pattern, most likely because of exposure to endogenous and exogenous triggers. The aim of the present report is to review the current knowledge of epidemiology, patterns of onset, and triggers of SCD and present directions for future research with a focus on coronary artery disease. (Curr Probl Cardiol 2011; 36:56-80.)

Original language	English
Pages (from-to)	56-80
Number of pages	25
Journal	Current problems in cardiology
Volume	36
Issue number	2
DOIs	https://doi.org/10.1016/j.cpcardiol.2011.01.002
Publication status	Published - Feb-2011

Keywords

ACUTE MYOCARDIAL-INFARCTION
VENTRICULAR SYSTOLIC DYSFUNCTION
MULTIPLE SOURCE SURVEILLANCE
ACUTE CARDIOVASCULAR-DISEASE
POPULATION-BASED ANALYSIS
CORONARY-ARTERY-DISEASE
BLOOD-PRESSURE
RISK STRATIFICATION
UNEXPECTED DEATH
HEART-DISEASE

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title = "Sudden Cardiac Death: Epidemiology, Circadian Variation, and Triggers",

abstract = "Sudden cardiac death (SCD) remains a major health issue accounting for over 5% of annual mortality in the Western world. There are several causes of SCD, most commonly, coronary artery disease. Although identifying the prodrome of SCD has attracted considerable interest, a large proportion of patients die before any medical contact is established. SCD onset seems to follow a circadian pattern, most likely because of exposure to endogenous and exogenous triggers. The aim of the present report is to review the current knowledge of epidemiology, patterns of onset, and triggers of SCD and present directions for future research with a focus on coronary artery disease. (Curr Probl Cardiol 2011; 36:56-80.)",

keywords = "ACUTE MYOCARDIAL-INFARCTION, VENTRICULAR SYSTOLIC DYSFUNCTION, MULTIPLE SOURCE SURVEILLANCE, ACUTE CARDIOVASCULAR-DISEASE, POPULATION-BASED ANALYSIS, CORONARY-ARTERY-DISEASE, BLOOD-PRESSURE, RISK STRATIFICATION, UNEXPECTED DEATH, HEART-DISEASE",

author = "Mahmoud, {Karim D.} and {de Smet}, {Bart J. G. L.} and Felix Zijlstra and Rihal, {Charanjit S.} and Holmes, {David R.}",

year = "2011",

month = feb,

doi = "10.1016/j.cpcardiol.2011.01.002",

language = "English",

volume = "36",

pages = "56--80",

journal = "Current problems in cardiology",

issn = "0146-2806",

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TY - JOUR

T1 - Sudden Cardiac Death

T2 - Epidemiology, Circadian Variation, and Triggers

AU - Mahmoud, Karim D.

AU - de Smet, Bart J. G. L.

AU - Zijlstra, Felix

AU - Rihal, Charanjit S.

AU - Holmes, David R.

PY - 2011/2

Y1 - 2011/2

N2 - Sudden cardiac death (SCD) remains a major health issue accounting for over 5% of annual mortality in the Western world. There are several causes of SCD, most commonly, coronary artery disease. Although identifying the prodrome of SCD has attracted considerable interest, a large proportion of patients die before any medical contact is established. SCD onset seems to follow a circadian pattern, most likely because of exposure to endogenous and exogenous triggers. The aim of the present report is to review the current knowledge of epidemiology, patterns of onset, and triggers of SCD and present directions for future research with a focus on coronary artery disease. (Curr Probl Cardiol 2011; 36:56-80.)

AB - Sudden cardiac death (SCD) remains a major health issue accounting for over 5% of annual mortality in the Western world. There are several causes of SCD, most commonly, coronary artery disease. Although identifying the prodrome of SCD has attracted considerable interest, a large proportion of patients die before any medical contact is established. SCD onset seems to follow a circadian pattern, most likely because of exposure to endogenous and exogenous triggers. The aim of the present report is to review the current knowledge of epidemiology, patterns of onset, and triggers of SCD and present directions for future research with a focus on coronary artery disease. (Curr Probl Cardiol 2011; 36:56-80.)

KW - ACUTE MYOCARDIAL-INFARCTION

KW - VENTRICULAR SYSTOLIC DYSFUNCTION

KW - MULTIPLE SOURCE SURVEILLANCE

KW - ACUTE CARDIOVASCULAR-DISEASE

KW - POPULATION-BASED ANALYSIS

KW - CORONARY-ARTERY-DISEASE

KW - BLOOD-PRESSURE

KW - RISK STRATIFICATION

KW - UNEXPECTED DEATH

KW - HEART-DISEASE

U2 - 10.1016/j.cpcardiol.2011.01.002

DO - 10.1016/j.cpcardiol.2011.01.002

M3 - Review article

SN - 0146-2806

VL - 36

SP - 56

EP - 80

JO - Current problems in cardiology

JF - Current problems in cardiology

IS - 2

ER -

Sudden Cardiac Death: Epidemiology, Circadian Variation, and Triggers

Abstract

Keywords

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