SULFASALAZINE INDUCED AGRANULOCYTOSIS TREATED WITH GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR

EJ KUIPERS, E VELLENGA, JTM DEWOLF, BPC HAZENBERG

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Abstract

We report the use of granulocyte-macrophage colony stimulating factor (GM-CSF) in a case of rheumatoid arthritis with sulfasalazine induced agranulocytosis, leading to a rapid bone marrow recovery within 7 days. This case and 2 others reported in the literature emphasize the need for further research into the possible role of GM-CSF in the treatment of drug induced agranulocytosis.

Original languageEnglish
Pages (from-to)621-622
Number of pages2
JournalJournal of Rheumatology
Volume19
Issue number4
Publication statusPublished - Apr-1992

Keywords

  • RHEUMATOID ARTHRITIS
  • SULFASALAZINE
  • AGRANULOCYTOSIS
  • GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR
  • RHEUMATOID-ARTHRITIS
  • SULPHASALAZINE
  • TOXICITY

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