TY - JOUR
T1 - Supportive care needs among head and neck cancer patients in the recovery phase from 6 months to 2 years after treatment
T2 - which factors matter?
AU - Molenaar, D
AU - Verdonck-de Leeuw, I M
AU - Lissenberg-Witte, B I
AU - Takes, R P
AU - de Bree, R
AU - Langendijk, J A
AU - Hardillo, J A
AU - Lamers, F
AU - Leemans, C R
AU - Jansen, F
N1 - © 2025. The Author(s).
PY - 2025/2/10
Y1 - 2025/2/10
N2 - PURPOSE: To investigate which demographic, personal, clinical, physical, psychological, social, lifestyle, and cancer-related quality of life (QoL) factors are associated with (changes in) supportive care needs (SCNs) from 6 months to 2 years after treatment in head and neck cancer (HNC) patients.METHODS: Data from the prospective NETherlands QUality of life and BIomedical Cohort (NET-QUBIC) study among HNC patients treated with curative intent was used. SCNs were measured using the Supportive Care Needs Survey 34-item Short-Form (SCNS-SF34) (6 months, 1 and 2 years after treatment) and the 11-item HNC-specific module (SCNS-HNC) (2 years). Multivariable linear mixed model analyses and linear regression analyses were used to study factors associated with changes in SCNs over time (SCNS-SF34) and the level of SCNs at 2 years follow-up (SCNS-SF34 and SCNS-HNC).RESULTS: Data from 483 patients was used. SCNs in the physical and daily living (PDL), psychological (PSY), and health system, information, and patient support (HSIPS) domains decreased significantly over time. At 2 years follow-up, the highest SCNs were reported regarding lack of energy/tiredness (10.8%). Changes in SCNs and the absolute level of SCNs at 2 years were associated with personal and clinical factors and post-treatment (6 months) with psychological, lifestyle, and cancer-related QoL factors.CONCLUSIONS: Personal, clinical, psychological, lifestyle, and cancer-related QoL factors were associated with SCNs. These results can be used to develop predictive models to personalize supportive care for HNC patients.IMPLICATIONS FOR CANCER SURVIVORS: SCNs decrease over time, but a subgroup of patients still presents with SCNs 2 years after treatment.
AB - PURPOSE: To investigate which demographic, personal, clinical, physical, psychological, social, lifestyle, and cancer-related quality of life (QoL) factors are associated with (changes in) supportive care needs (SCNs) from 6 months to 2 years after treatment in head and neck cancer (HNC) patients.METHODS: Data from the prospective NETherlands QUality of life and BIomedical Cohort (NET-QUBIC) study among HNC patients treated with curative intent was used. SCNs were measured using the Supportive Care Needs Survey 34-item Short-Form (SCNS-SF34) (6 months, 1 and 2 years after treatment) and the 11-item HNC-specific module (SCNS-HNC) (2 years). Multivariable linear mixed model analyses and linear regression analyses were used to study factors associated with changes in SCNs over time (SCNS-SF34) and the level of SCNs at 2 years follow-up (SCNS-SF34 and SCNS-HNC).RESULTS: Data from 483 patients was used. SCNs in the physical and daily living (PDL), psychological (PSY), and health system, information, and patient support (HSIPS) domains decreased significantly over time. At 2 years follow-up, the highest SCNs were reported regarding lack of energy/tiredness (10.8%). Changes in SCNs and the absolute level of SCNs at 2 years were associated with personal and clinical factors and post-treatment (6 months) with psychological, lifestyle, and cancer-related QoL factors.CONCLUSIONS: Personal, clinical, psychological, lifestyle, and cancer-related QoL factors were associated with SCNs. These results can be used to develop predictive models to personalize supportive care for HNC patients.IMPLICATIONS FOR CANCER SURVIVORS: SCNs decrease over time, but a subgroup of patients still presents with SCNs 2 years after treatment.
U2 - 10.1007/s11764-025-01753-0
DO - 10.1007/s11764-025-01753-0
M3 - Article
C2 - 39928280
SN - 1932-2259
JO - Journal of cancer survivorship-Research and practice
JF - Journal of cancer survivorship-Research and practice
ER -