Surgeon-Performed Ultrasound as Preoperative Localization Study in Patients with Primary Hyperparathyroidism

T. M. van Ginhoven, A. N. Morks, T. Schepers, P. W. de Graaf, P. C. Smit*

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    7 Citations (Scopus)

    Abstract

    Background: Minimally invasive parathyroidectomy is the treatment of choice for single-gland primary hyperparathyroidism. However, the exact location of the abnormal gland has to be established. Sestamibi scintigraphy, computed tomography and ultrasound (US) are commonly used modalities. We describe our experience in a non-academic center with surgeon-performed US (S-US) of the neck as preoperative localization study in patients with primary hyperparathyroidism (PHPT). Methods: Patients with a biochemically proven diagnosis of PHPT and preoperative S-US were included. Data were recorded prospectively. Perioperative gland location was compared to the preoperative S-US to determine sensitivity, specificity and accuracy rates. Results: Two of the 50 patients who underwent S-US were not subjected to surgery. In 85% of the patients analyzed by S-US, the appropriate abnormal gland(s) were identified. In 11%, no gland was identified, but abnormal glands were found during surgery. Sensitivity of S-US in our hospital is 85%, with a positive predictive value of 97%. Conclusions: We achieved a satisfactory sensitivity rate. S-US provides anatomic information to the surgeon which enables a more detailed operation planning, and it is a valuable diagnostic modality for patients with PHPT in our opinion. We hope that our data encourage other centers to implement this technique as well. Copyright (C) 2011 S. Karger AG, Basel

    Original languageEnglish
    Pages (from-to)70-74
    Number of pages5
    JournalEuropean surgical research
    Volume47
    Issue number2
    DOIs
    Publication statusPublished - 2011

    Keywords

    • Minimally invasive approach
    • Parathyroid hormone
    • Primary hyperparathyroidism
    • Ultrasound
    • SPORADIC PRIMARY HYPERPARATHYROIDISM
    • BILATERAL CERVICAL EXPLORATION
    • TC-99M SESTAMIBI MODALITY
    • GUIDE FOCUSED EXPLORATION
    • NECK EXPLORATION
    • PARATHYROID SCINTIGRAPHY
    • COMPUTED-TOMOGRAPHY
    • SELECT PATIENTS
    • CLINICAL-TRIAL
    • ULTRASONOGRAPHY

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