Synthesis and Absolute Configuration of Enantiomerically Pure Vitamin K3 2,3-Epoxide

Günther Snatzke; Hans Wijnberg; Bernard Feringa; Bea G. Marsman; Ben Greydanus; Henk Pluim

doi:10.1021/jo01309a005

Synthesis and Absolute Configuration of Enantiomerically Pure Vitamin K3 2,3-Epoxide

Günther Snatzke, Hans Wijnberg, Bernard Feringa, Bea G. Marsman, Ben Greydanus, Henk Pluim

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

The 2,3-epoxide of vitamin K3 (menadione, 1) has been prepared in enantiomerically pure form, and the absolute configuration has been deduced from the CD spectrum. The compound with the negative Cotton effect between 340 and 400 nm has the 2R,3S configuration.

Original language	English
Pages (from-to)	4094-4096
Number of pages	3
Journal	Journal of Organic Chemistry
Volume	45
Issue number	21
DOIs	https://doi.org/10.1021/jo01309a005
Publication status	Published - 1980

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title = "Synthesis and Absolute Configuration of Enantiomerically Pure Vitamin K3 2,3-Epoxide",

abstract = "The 2,3-epoxide of vitamin K3 (menadione, 1) has been prepared in enantiomerically pure form, and the absolute configuration has been deduced from the CD spectrum. The compound with the negative Cotton effect between 340 and 400 nm has the 2R,3S configuration.",

author = "G{\"u}nther Snatzke and Hans Wijnberg and Bernard Feringa and Marsman, {Bea G.} and Ben Greydanus and Henk Pluim",

note = "Relation: http://www.rug.nl/scheikunde/ date_submitted:2005 Rights: University of Groningen. Stratingh Institute",

year = "1980",

doi = "10.1021/jo01309a005",

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issn = "0022-3263",

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AU - Snatzke, Günther

AU - Wijnberg, Hans

AU - Feringa, Bernard

AU - Marsman, Bea G.

AU - Greydanus, Ben

AU - Pluim, Henk

N1 - Relation: http://www.rug.nl/scheikunde/ date_submitted:2005 Rights: University of Groningen. Stratingh Institute

PY - 1980

Y1 - 1980

N2 - The 2,3-epoxide of vitamin K3 (menadione, 1) has been prepared in enantiomerically pure form, and the absolute configuration has been deduced from the CD spectrum. The compound with the negative Cotton effect between 340 and 400 nm has the 2R,3S configuration.

AB - The 2,3-epoxide of vitamin K3 (menadione, 1) has been prepared in enantiomerically pure form, and the absolute configuration has been deduced from the CD spectrum. The compound with the negative Cotton effect between 340 and 400 nm has the 2R,3S configuration.

U2 - 10.1021/jo01309a005

DO - 10.1021/jo01309a005

M3 - Article

SN - 0022-3263

VL - 45

SP - 4094

EP - 4096

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 21

ER -

Synthesis and Absolute Configuration of Enantiomerically Pure Vitamin K3 2,3-Epoxide

Abstract

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