Synthesis and Absolute Configuration of Enantiomerically Pure Vitamin K3 2,3-Epoxide

Günther Snatzke; Hans Wijnberg; Bernard Feringa; Bea G. Marsman; Ben Greydanus; Henk Pluim

doi:10.1021/jo01309a005

Synthesis and Absolute Configuration of Enantiomerically Pure Vitamin K3 2,3-Epoxide

Günther Snatzke, Hans Wijnberg, Bernard Feringa, Bea G. Marsman, Ben Greydanus, Henk Pluim

Research output: Contribution to journal › Article › Academic › peer-review

23 Citations (Scopus)

Abstract

The 2,3-epoxide of vitamin K3 (menadione, 1) has been prepared in enantiomerically pure form, and the absolute configuration has been deduced from the CD spectrum. The compound with the negative Cotton effect between 340 and 400 nm has the 2R,3S configuration.

Original language	English
Pages (from-to)	4094-4096
Number of pages	3
Journal	Journal of Organic Chemistry
Volume	45
Issue number	21
DOIs	https://doi.org/10.1021/jo01309a005
Publication status	Published - 1980

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title = "Synthesis and Absolute Configuration of Enantiomerically Pure Vitamin K3 2,3-Epoxide",

abstract = "The 2,3-epoxide of vitamin K3 (menadione, 1) has been prepared in enantiomerically pure form, and the absolute configuration has been deduced from the CD spectrum. The compound with the negative Cotton effect between 340 and 400 nm has the 2R,3S configuration.",

author = "G{\"u}nther Snatzke and Hans Wijnberg and Bernard Feringa and Marsman, {Bea G.} and Ben Greydanus and Henk Pluim",

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AU - Wijnberg, Hans

AU - Feringa, Bernard

AU - Marsman, Bea G.

AU - Greydanus, Ben

AU - Pluim, Henk

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AB - The 2,3-epoxide of vitamin K3 (menadione, 1) has been prepared in enantiomerically pure form, and the absolute configuration has been deduced from the CD spectrum. The compound with the negative Cotton effect between 340 and 400 nm has the 2R,3S configuration.

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DO - 10.1021/jo01309a005

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JO - The Journal of Organic Chemistry

JF - The Journal of Organic Chemistry

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