Abstract
1,6-Dichlorohexa-2,4-diyne undergoes nickel-catalyzed double substitution with aryl and alkenyl Grignard reagents to provide substituted ene-yne-enes. The reaction is formally an extension of the well-described S(N)2'-allylic and -propargylic substitution reactions but the mechanism is considerably more complex. The products might function as building blocks for conjugated polymers.
| Original language | English |
|---|---|
| Article number | C7CY00429J |
| Pages (from-to) | 2347-2355 |
| Number of pages | 9 |
| Journal | Catalysis Science & Technology |
| Volume | 7 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 7-Jun-2017 |
Keywords
- ASYMMETRIC ALLYLIC ALKYLATION
- ENANTIOSELECTIVE SYNTHESIS
- GRIGNARD-REAGENTS
- ALKYLZINC REAGENTS
- ORGANIC HALIDES
- COPPER
- COMPLEXES
- BOND
- DESYMMETRIZATION
- POLYDIACETYLENES
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CCDC 1519007: Experimental Crystal Structure Determination
Wang, G. (Contributor), Lindeboom, E. (Contributor), Heerewaarden , van, C. (Contributor) & Minnaard, A. (Contributor), University of Groningen, 24-Nov-2016
DOI: 10.5517/ccdc.csd.cc1mzn7h
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