Abstract
A critical aspect in the bottom-up construction of a synthetic minimal cell is to develop an entity that is capable of self-reproduction. A key role in this process is the expansion and division of the boundary layer that surrounds the compartment, a process in which content loss has to be avoided and the barrier function maintained. Here, we describe the latest developments regarding self-reproduction of a boundary layer with a focus on the growth and division of phospholipid-based membranes in the context of a synthetic minimal cell.
Original language | English |
---|---|
Article number | 02955 |
Pages (from-to) | 5293-5303 |
Number of pages | 11 |
Journal | ACS Omega |
Volume | 4 |
Issue number | 3 |
DOIs | |
Publication status | Published - 31-Mar-2019 |
Keywords
- synthetic biology
- minimal cell
- SELF-REPRODUCTION
- MEMBRANE PHOSPHOLIPID-SYNTHESIS
- IN-VITRO RECONSTITUTION
- FATTY-ACID SYNTHASES
- ESCHERICHIA-COLI
- FLIP-FLOP
- PROTEIN TRANSLOCATION
- BACTERIAL LIPIDS
- DIVISION
- VESICLES
- MODEL