TY - PAT
T1 - Synthetic peptides blocking sars-cov-2 (covid-19), and compositions, methods and uses related thereto
AU - Sadremomtaz, Afsaneh
AU - Groves, Matthew Robert
AU - van Goor, Harm
AU - Doti, Nunzianna
AU - Monti, Alessandra
PY - 2022/9/1
Y1 - 2022/9/1
N2 - The invention relates to the field of medicine and therapeutically active peptides, more specifically to the design of peptides that antagonise Angiotensin-Converting Enzyme-2 (ACE-2) interaction with the receptor binding spike protein of SARS-CoV-2. Provided is a peptidic compound comprising or consisting of an amino acid sequence selected from the following: IYALLENAEDYNLVN, SRDKHEEHEKENDRGQ, DKFNHEAEDLFYQSSLASWNYNT, IEEQAKTFLDKFQHEVEEIYWQS, QDKHEEDYQMYNKGDKED and IDENARSYIDKFQHDAEEMWYQ, or an amide, an ester or a salt thereof.
AB - The invention relates to the field of medicine and therapeutically active peptides, more specifically to the design of peptides that antagonise Angiotensin-Converting Enzyme-2 (ACE-2) interaction with the receptor binding spike protein of SARS-CoV-2. Provided is a peptidic compound comprising or consisting of an amino acid sequence selected from the following: IYALLENAEDYNLVN, SRDKHEEHEKENDRGQ, DKFNHEAEDLFYQSSLASWNYNT, IEEQAKTFLDKFQHEVEEIYWQS, QDKHEEDYQMYNKGDKED and IDENARSYIDKFQHDAEEMWYQ, or an amide, an ester or a salt thereof.
M3 - Patent
M1 - WO2022182241
Y2 - 2022/02/25
ER -