Synthetic peptides blocking sars-cov-2 (covid-19), and compositions, methods and uses related thereto

Afsaneh Sadremomtaz (Inventor), Matthew Robert Groves (Inventor), Harm van Goor (Inventor), Nunzianna Doti (Inventor), Alessandra Monti (Inventor)

Research output: Patent

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Abstract

The invention relates to the field of medicine and therapeutically active peptides, more specifically to the design of peptides that antagonise Angiotensin-Converting Enzyme-2 (ACE-2) interaction with the receptor binding spike protein of SARS-CoV-2. Provided is a peptidic compound comprising or consisting of an amino acid sequence selected from the following: IYALLENAEDYNLVN, SRDKHEEHEKENDRGQ, DKFNHEAEDLFYQSSLASWNYNT, IEEQAKTFLDKFQHEVEEIYWQS, QDKHEEDYQMYNKGDKED and IDENARSYIDKFQHDAEEMWYQ, or an amide, an ester or a salt thereof.
Original languageEnglish
Patent numberWO2022182241
Priority date26/02/2020
Filing date25/02/2022
Publication statusPublished - 1-Sept-2022

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