Abstract
Since 1989, granulocyte-macrophage and granulocyte colony-stimulating factors (GM-CSF, G-CSF) have been increasingly applied in the treatment of drug-induced agranulocytosis. In order to evaluate the effectiveness of GM-CSF and G-CSF in the treatment of drug-induced agranulocytosis, we have studied all reported cases (n = 70) treated with GM-CSF and G-CSF, including ten patients treated during the last 2 years in The Netherlands. The results demonstrate that patients with a severe granulocytopenia (
| Original language | English |
|---|---|
| Pages (from-to) | 2031-2036 |
| Number of pages | 6 |
| Journal | Leukemia |
| Volume | 8 |
| Issue number | 12 |
| Publication status | Published - Dec-1994 |
Keywords
- COLONY-STIMULATING FACTOR
- CLOZAPINE-INDUCED AGRANULOCYTOSIS
- SULFASALAZINE-INDUCED AGRANULOCYTOSIS
- GM-CSF
- NEUTROPENIA
- PATIENT
- FILGRASTIM
- RECOVERY
- THERAPY