The assessment of frailty and malnutrition in vascular surgery

    Research output: ThesisThesis fully internal (DIV)

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    Abstract

    The world is faced with an ageing population. Compared to other medical specialties, the inflow of elderly patients will have its highest impact in vascular surgery. In this ageing vascular patient population, it is crucial to select which patients will benefit the most of a vascular intervention in terms of quality of life and survival. Over the past decades, it became clear that biological age provides more information about a patients’ fitness than chronological age. One way of approaching biological ageing is by using the frailty syndrome to describe the most vulnerable elderly patients.The frailty syndrome contains several physical domains, for example visual impairment, hearing impairment, comorbidities, physical functioning and nutritional status. Both the roles of frailty and malnutrition in vascular surgery patients are investigated in this thesis. We found that 24% of the patients were at medium to high risk for malnutrition and that these patients are more prone to develop postoperative complications. Secondly, we found that preoperative frailty leads to more postoperative complications and a worse 5-year survival. Moreover, frailty is dynamic in vascular surgery patients and is affected by the surgical intervention. These results wil hopefully lead to a better estimation of postoperative outcomes in terms of complications and functioning. The growing share of elderly patients in the vascular clinic demands an adapted, multidisciplinary approach.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • University of Groningen
    Supervisors/Advisors
    • Pol, Robert, Supervisor
    • Zeebregts, Clark, Supervisor
    • Middeldorp, Saskia, Assessment committee, External person
    • de Vries, Jean-Paul, Assessment committee
    • Klaase, Joost, Assessment committee
    Award date6-Sept-2023
    Place of Publication[Groningen]
    Publisher
    DOIs
    Publication statusPublished - 2023

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