TY - JOUR
T1 - The association between smoking behaviour, social cognition and social functioning in patients with a non-affective psychotic disorder
T2 - A prospective follow-up study
AU - Dekker, Tobias E G
AU - van der Heijden, Heleen S
AU - Schirmbeck, Frederike
AU - van Amelsvoort, Therese
AU - Bartels-Velthuis, Agna A
AU - Simons, Claudia J P
AU - de Haan, Lieuwe
AU - Vermeulen, Jentien M
N1 - © 2021 The Authors. Published by Elsevier Inc.
PY - 2021/12
Y1 - 2021/12
N2 - Introduction: In patients with psychotic disorders, both tobacco smoking and deficits in social cognition and social functioning are highly prevalent. However, little is known about their relationship in psychosis. The authors sought to evaluate the multi-cross-sectional and longitudinal associations between tobacco smoking, social cognition and social functioning in a large prospective study.Methods: This study was performed within the Genetic Risk and Outcome of Psychosis (GROUP) Study, a cohort study conducted in patients with non-affective psychosis (N = 1074), their unaffected siblings (N = 1047) and healthy controls (N = 549). At baseline, three years and six years of follow-up, data on tobacco smoking (using the Composite International Diagnostic Review), social cognition (emotion processing and theory of mind) and social functioning were collected. To assess associations between tobacco smoking and social cognition or social functioning, multivariate linear mixed-effects models and multiple linear regression models were used. Bon-ferroni correction for multiple testing was applied.Results: A significant positive association was found between smoking and emotion processing (as part of social cognition) in the patient group (estimate = 1.96, SE = 0.6, p = 0.003). However, smoking was significantly negatively associated with participating in pro-social activities compared with non-smoking (estimate =-2.55, SE = 0.9, p = 0.004). Change in smoking behaviour was not associated with social cognition or social functioning in the longitudinal analyses.Conclusion: Findings indicate that smoking patients with a non-affective psychotic disorder slightly outperformed their non-smoking peers on a task on social cognition, but participated less in pro-social activities. Commencement or cessation of smoking was not related to social cognition or functioning.
AB - Introduction: In patients with psychotic disorders, both tobacco smoking and deficits in social cognition and social functioning are highly prevalent. However, little is known about their relationship in psychosis. The authors sought to evaluate the multi-cross-sectional and longitudinal associations between tobacco smoking, social cognition and social functioning in a large prospective study.Methods: This study was performed within the Genetic Risk and Outcome of Psychosis (GROUP) Study, a cohort study conducted in patients with non-affective psychosis (N = 1074), their unaffected siblings (N = 1047) and healthy controls (N = 549). At baseline, three years and six years of follow-up, data on tobacco smoking (using the Composite International Diagnostic Review), social cognition (emotion processing and theory of mind) and social functioning were collected. To assess associations between tobacco smoking and social cognition or social functioning, multivariate linear mixed-effects models and multiple linear regression models were used. Bon-ferroni correction for multiple testing was applied.Results: A significant positive association was found between smoking and emotion processing (as part of social cognition) in the patient group (estimate = 1.96, SE = 0.6, p = 0.003). However, smoking was significantly negatively associated with participating in pro-social activities compared with non-smoking (estimate =-2.55, SE = 0.9, p = 0.004). Change in smoking behaviour was not associated with social cognition or social functioning in the longitudinal analyses.Conclusion: Findings indicate that smoking patients with a non-affective psychotic disorder slightly outperformed their non-smoking peers on a task on social cognition, but participated less in pro-social activities. Commencement or cessation of smoking was not related to social cognition or functioning.
KW - Tobacco
KW - Emotion processing
KW - Theory of mind
KW - Schizophrenia
KW - 1ST EPISODE PSYCHOSIS
KW - TOBACCO SMOKING
KW - HIGH-RISK
KW - SCHIZOPHRENIA
KW - SCALE
KW - METAANALYSIS
KW - INDIVIDUALS
KW - IDENTIFICATION
KW - ADJUSTMENT
KW - SYMPTOMS
U2 - 10.1016/j.scog.2021.100206
DO - 10.1016/j.scog.2021.100206
M3 - Article
C2 - 34258239
SN - 2215-0013
VL - 26
JO - Schizophrenia Research: Cognition
JF - Schizophrenia Research: Cognition
M1 - 100206
ER -