The Changing Spectrum of Neonatal Hepatitis

Nedim Hadzic*, Henkjan J. Verkade

*Corresponding author for this work

Research output: Contribution to journalEditorialAcademicpeer-review

5 Citations (Scopus)

Abstract

Neonatal hepatitis (NH) is a default diagnosis reached after excluding other more specific causes of prolonged neonatal cholestasis (PNC). The purpose of this brief review is to highlight the expanding spectrum of diagnoses causing PNC of infancy and to address emerging clinical dilemmas about the role of conventional clinical tests such as liver biopsy or dynamic hepatobiliary scintigraphy in the new era. Novel entities and overlapping metabolic conditions are listed, with a hope to increase awareness of practising paediatricians and direct more specific investigations.

Original languageEnglish
Pages (from-to)316-319
Number of pages4
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume63
Issue number3
DOIs
Publication statusPublished - Sep-2016

Keywords

  • FAMILIAL INTRAHEPATIC CHOLESTASIS
  • CYSTIC-FIBROSIS GENE
  • BILIARY ATRESIA
  • LIVER-DISEASE
  • RENAL DYSFUNCTION
  • MASS-SPECTROMETRY
  • MUTATIONS
  • DEFICIENCY
  • INFANTS
  • IDENTIFICATION

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