This thesis provides a detailed description of the HIV-1 epidemic and treatment of HIV-1 infected individuals in Curaçao. We conclude that the immunological, virological and clinical responses to cART in Curaçao are sub-optimal due to late cART initiation and low rates of retention in care. Given the results presented in this thesis, we suggest creating a HIV care model aimed at maximizing the therapeutic and preventive effects of cART by focusing on early identification of HIV-1 infection followed by immediate cART initiation with life-long monitoring. Importantly, these strategies require the integration of HIV care into primary health care provision in Curaçao and tasks shifting from infectious disease medical specialists to general practitioners.
|Translated title of the contribution||De Curaçao Cohort Studies: Een analyse van de implementatie van antiretrovirale combinatie therapie in Curaçao|
|Qualification||Doctor of Philosophy|
|Place of Publication||[S.l.]|
|Publication status||Published - 2015|