The Curaçao Cohort Studies: An analysis of the implementation of combination antiretroviral therapy in Curaçao

Hillegonda de Groot-Hermanides

    Research output: ThesisThesis fully internal (DIV)

    2291 Downloads (Pure)

    Abstract

    This thesis provides a detailed description of the HIV-1 epidemic and treatment of HIV-1 infected individuals in Curaçao. We conclude that the immunological, virological and clinical responses to cART in Curaçao are sub-optimal due to late cART initiation and low rates of retention in care. Given the results presented in this thesis, we suggest creating a HIV care model aimed at maximizing the therapeutic and preventive effects of cART by focusing on early identification of HIV-1 infection followed by immediate cART initiation with life-long monitoring. Importantly, these strategies require the integration of HIV care into primary health care provision in Curaçao and tasks shifting from infectious disease medical specialists to general practitioners.
    Translated title of the contributionDe Curaçao Cohort Studies: Een analyse van de implementatie van antiretrovirale combinatie therapie in Curaçao
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • University of Groningen
    Supervisors/Advisors
    • Duits, Ashley, Supervisor
    • de Wolf, Frank, Supervisor, External person
    • van der Werf, Tjip, Assessment committee
    • Prins, J.M., Assessment committee, External person
    • Goudsmit, J., Assessment committee, External person
    Award date7-Jan-2015
    Place of Publication[S.l.]
    Publisher
    Print ISBNs9789461087102
    Publication statusPublished - 2015

    Cite this