TY - CHAP
T1 - The Disease-Modifying Role of Taurine and Its Therapeutic Potential in Coronavirus Disease 2019 (COVID-19)
AU - van Eijk, Larissa E.
AU - Offringa, Annette K.
AU - Bernal, Maria-Elena
AU - Bourgonje, Arno R.
AU - van Goor, Harry
AU - Hillebrands, Jan-Luuk
PY - 2022/7/27
Y1 - 2022/7/27
N2 - Taurine is an amino sulfonic acid that is implicated in numerous physiological functions, including the regulation of oxidative stress, which plays an important role in coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), together with other pathophysiological processes. The recent finding of decreased serum taurine levels in SARS-CoV-2-infected patients, in tandem with its potential modulatory role in COVID-19 due to its antiviral, antioxidant, anti-inflammatory, and vascular-related effects, provides a rationale for considering taurine as a beneficial supplement in patients suffering from COVID-19. Here, we reviewed the potential disease-modifying effects of taurine and combined these with the current knowledge on COVID-19 to clarify the potential role of taurine in this respiratory disease.
AB - Taurine is an amino sulfonic acid that is implicated in numerous physiological functions, including the regulation of oxidative stress, which plays an important role in coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), together with other pathophysiological processes. The recent finding of decreased serum taurine levels in SARS-CoV-2-infected patients, in tandem with its potential modulatory role in COVID-19 due to its antiviral, antioxidant, anti-inflammatory, and vascular-related effects, provides a rationale for considering taurine as a beneficial supplement in patients suffering from COVID-19. Here, we reviewed the potential disease-modifying effects of taurine and combined these with the current knowledge on COVID-19 to clarify the potential role of taurine in this respiratory disease.
U2 - 10.1007/978-3-030-93337-1_1
DO - 10.1007/978-3-030-93337-1_1
M3 - Chapter
SN - 978-3-030-93336-4
SP - 3
EP - 21
BT - Taurine 12
A2 - Schaffer, Stephen W.
A2 - El Idrissi, Abdeslem
A2 - Murakami, Shigeru
PB - Springer International Publishing, Cham, Switzerland
ER -