The Disease-Modifying Role of Taurine and Its Therapeutic Potential in Coronavirus Disease 2019 (COVID-19)

Larissa E. van Eijk, Annette K. Offringa, Maria-Elena Bernal, Arno R. Bourgonje, Harry van Goor, Jan-Luuk Hillebrands

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

2 Citations (Scopus)
216 Downloads (Pure)


Taurine is an amino sulfonic acid that is implicated in numerous physiological functions, including the regulation of oxidative stress, which plays an important role in coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), together with other pathophysiological processes. The recent finding of decreased serum taurine levels in SARS-CoV-2-infected patients, in tandem with its potential modulatory role in COVID-19 due to its antiviral, antioxidant, anti-inflammatory, and vascular-related effects, provides a rationale for considering taurine as a beneficial supplement in patients suffering from COVID-19. Here, we reviewed the potential disease-modifying effects of taurine and combined these with the current knowledge on COVID-19 to clarify the potential role of taurine in this respiratory disease.
Original languageEnglish
Title of host publicationTaurine 12
Subtitle of host publicationA Conditionally Essential Amino Acid
EditorsStephen W. Schaffer, Abdeslem El Idrissi, Shigeru Murakami
PublisherSpringer International Publishing, Cham, Switzerland
Number of pages19
ISBN (Electronic)978-3-030-93337-1
ISBN (Print)978-3-030-93336-4
Publication statusPublished - 27-Jul-2022

Publication series

ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

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