The efficacy of Xialine® in patients with xerostomia resulting from radiotherapy for head and neck cancer: a pilot-study

Anke Petra Jellema; Hans  Langendijk; Lester Bergenhenegouwen; Willy van der Reijden; Rene Leemans; Ludy Smeele; Berend J. Slotman

doi:10.1016/S0167-8140(01)00336-X

The efficacy of Xialine® in patients with xerostomia resulting from radiotherapy for head and neck cancer: a pilot-study

Anke Petra Jellema, Hans Langendijk, Lester Bergenhenegouwen, Willy van der Reijden, Rene Leemans, Ludy Smeele, Berend J. Slotman

Research output: Contribution to journal › Article › Academic › peer-review

24 Citations (Scopus)

Abstract

Changes in subjective sensations due to xerostomia before and after administration of Xialine(R), a xanthan gum-based saliva substitute, were evaluated in 30 patients with radiation-induced xerostomia using the QLQ-H&N35. Xerostomia in general decreased with both Xialine(R) and placebo to almost the same degree. A trend was seen for Xialine(R) to improve problems with speech and senses. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

Original language	English
Pages (from-to)	157-160
Number of pages	4
Journal	Radiotherapy and Oncology
Volume	59
Issue number	2
DOIs	https://doi.org/10.1016/S0167-8140(01)00336-X
Publication status	Published - 1-May-2001
Externally published	Yes

Keywords

xerostomia
saliva substitute
quality of life
head and neck cancer
irradiation
RADIATION-INDUCED XEROSTOMIA
SALIVA SUBSTITUTES
DRY MOUTH
LIFE
PILOCARPINE
QUESTIONNAIRE
MODULE

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Cite this

@article{c777506c34734341948635a064c85b6e,

title = "The efficacy of Xialine{\textregistered} in patients with xerostomia resulting from radiotherapy for head and neck cancer: a pilot-study",

abstract = "Changes in subjective sensations due to xerostomia before and after administration of Xialine(R), a xanthan gum-based saliva substitute, were evaluated in 30 patients with radiation-induced xerostomia using the QLQ-H&N35. Xerostomia in general decreased with both Xialine(R) and placebo to almost the same degree. A trend was seen for Xialine(R) to improve problems with speech and senses. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.",

keywords = "xerostomia, saliva substitute, quality of life, head and neck cancer, irradiation, RADIATION-INDUCED XEROSTOMIA, SALIVA SUBSTITUTES, DRY MOUTH, LIFE, PILOCARPINE, QUESTIONNAIRE, MODULE",

author = "Jellema, {Anke Petra} and Hans Langendijk and Lester Bergenhenegouwen and {van der Reijden}, Willy and Rene Leemans and Ludy Smeele and Slotman, {Berend J.}",

year = "2001",

month = may,

day = "1",

doi = "10.1016/S0167-8140(01)00336-X",

language = "English",

volume = "59",

pages = "157--160",

journal = "Radiotherapy and Oncology",

issn = "0167-8140",

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TY - JOUR

T1 - The efficacy of Xialine® in patients with xerostomia resulting from radiotherapy for head and neck cancer

T2 - a pilot-study

AU - Jellema, Anke Petra

AU - Langendijk, Hans

AU - Bergenhenegouwen, Lester

AU - van der Reijden, Willy

AU - Leemans, Rene

AU - Smeele, Ludy

AU - Slotman, Berend J.

PY - 2001/5/1

Y1 - 2001/5/1

N2 - Changes in subjective sensations due to xerostomia before and after administration of Xialine(R), a xanthan gum-based saliva substitute, were evaluated in 30 patients with radiation-induced xerostomia using the QLQ-H&N35. Xerostomia in general decreased with both Xialine(R) and placebo to almost the same degree. A trend was seen for Xialine(R) to improve problems with speech and senses. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

AB - Changes in subjective sensations due to xerostomia before and after administration of Xialine(R), a xanthan gum-based saliva substitute, were evaluated in 30 patients with radiation-induced xerostomia using the QLQ-H&N35. Xerostomia in general decreased with both Xialine(R) and placebo to almost the same degree. A trend was seen for Xialine(R) to improve problems with speech and senses. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

KW - xerostomia

KW - saliva substitute

KW - quality of life

KW - head and neck cancer

KW - irradiation

KW - RADIATION-INDUCED XEROSTOMIA

KW - SALIVA SUBSTITUTES

KW - DRY MOUTH

KW - LIFE

KW - PILOCARPINE

KW - QUESTIONNAIRE

KW - MODULE

U2 - 10.1016/S0167-8140(01)00336-X

DO - 10.1016/S0167-8140(01)00336-X

M3 - Article

SN - 0167-8140

VL - 59

SP - 157

EP - 160

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

IS - 2

ER -