The efficacy of Xialine® in patients with xerostomia resulting from radiotherapy for head and neck cancer: a pilot-study

Anke Petra Jellema, Hans Langendijk, Lester Bergenhenegouwen, Willy van der Reijden, Rene Leemans, Ludy Smeele, Berend J. Slotman

Research output: Contribution to journalArticleAcademicpeer-review

42 Citations (Scopus)

Abstract

Changes in subjective sensations due to xerostomia before and after administration of Xialine(R), a xanthan gum-based saliva substitute, were evaluated in 30 patients with radiation-induced xerostomia using the QLQ-H&N35. Xerostomia in general decreased with both Xialine(R) and placebo to almost the same degree. A trend was seen for Xialine(R) to improve problems with speech and senses. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)157-160
Number of pages4
JournalRadiotherapy and Oncology
Volume59
Issue number2
DOIs
Publication statusPublished - 1-May-2001
Externally publishedYes

Keywords

  • xerostomia
  • saliva substitute
  • quality of life
  • head and neck cancer
  • irradiation
  • RADIATION-INDUCED XEROSTOMIA
  • SALIVA SUBSTITUTES
  • DRY MOUTH
  • LIFE
  • PILOCARPINE
  • QUESTIONNAIRE
  • MODULE

Cite this