TY - JOUR
T1 - The EPTN consensus-based atlas for CT- and MR-based contouring in neuro-oncology
AU - Taskforce European Particle
AU - Eekers, Danielle B. P.
AU - in 't Ven, Lieke
AU - Roelofs, Erik
AU - Postma, Alida
AU - Alapetite, Claire
AU - Burnet, Neil G.
AU - Calugaru, Valentin
AU - Compter, Inge
AU - Coremans, Ida E. M.
AU - Hoyer, Morton
AU - Lambrecht, Maarten
AU - Nystrom, Petra Witt
AU - Romero, Alejandra Mendez
AU - Paulsen, Frank
AU - Perpar, Ana
AU - de Ruysscher, Dirk
AU - Renard, Laurette
AU - Timmermann, Beate
AU - Vitek, Pavel
AU - Weber, Damien C.
AU - van der Weide, Hiske L.
AU - Whitfield, Gillian A.
AU - Wiggenraad, Ruud
AU - Troost, Esther G. C.
PY - 2018/7
Y1 - 2018/7
N2 - Purpose: To create a digital, online atlas for organs at risk (OAR) delineation in neuro-oncology based on high-quality computed tomography (Cr) and magnetic resonance (MR) imaging.Methods: CT and 3 Tesla (3T) MR images (slice thickness 1 mm with intravenous contrast agent) were obtained from the same patient and subsequently fused. In addition, a 7T MR without intravenous contrast agent was obtained from a healthy volunteer. Based on discussion between experienced radiation oncologists, the clinically relevant organs at risk (OARs) to be included in the atlas for neuro-oncology were determined, excluding typical head and neck OARs previously published. The draft atlas was delineated by a senior radiation oncologist, 2 residents in radiation oncology, and a senior neuro-radiologist incorporating relevant available literature. The proposed atlas was then critically reviewed and discussed by European radiation oncologists until consensus was reached.Results: The online atlas includes one CT-scan at two different window settings and one MR scan (3T) showing the OARs in axial, coronal and sagittal view. This manuscript presents the three-dimensional descriptions of the fifteen consensus OARs for neuro-oncology. Among these is a new OAR relevant for neuro-cognition, the posterior cerebellum (illustrated on 7T MR images).Conclusion: In order to decrease inter- and intra-observer variability in delineating OARs relevant for neuro-oncology and thus derive consistent dosimetric data, we propose this atlas to be used in photon and particle therapy. The atlas is available online at w.cancerdata.c and will be updated whenever required. (C) 2017 The Authors. Published by Elsevier B.V.
AB - Purpose: To create a digital, online atlas for organs at risk (OAR) delineation in neuro-oncology based on high-quality computed tomography (Cr) and magnetic resonance (MR) imaging.Methods: CT and 3 Tesla (3T) MR images (slice thickness 1 mm with intravenous contrast agent) were obtained from the same patient and subsequently fused. In addition, a 7T MR without intravenous contrast agent was obtained from a healthy volunteer. Based on discussion between experienced radiation oncologists, the clinically relevant organs at risk (OARs) to be included in the atlas for neuro-oncology were determined, excluding typical head and neck OARs previously published. The draft atlas was delineated by a senior radiation oncologist, 2 residents in radiation oncology, and a senior neuro-radiologist incorporating relevant available literature. The proposed atlas was then critically reviewed and discussed by European radiation oncologists until consensus was reached.Results: The online atlas includes one CT-scan at two different window settings and one MR scan (3T) showing the OARs in axial, coronal and sagittal view. This manuscript presents the three-dimensional descriptions of the fifteen consensus OARs for neuro-oncology. Among these is a new OAR relevant for neuro-cognition, the posterior cerebellum (illustrated on 7T MR images).Conclusion: In order to decrease inter- and intra-observer variability in delineating OARs relevant for neuro-oncology and thus derive consistent dosimetric data, we propose this atlas to be used in photon and particle therapy. The atlas is available online at w.cancerdata.c and will be updated whenever required. (C) 2017 The Authors. Published by Elsevier B.V.
KW - Atlas for neuro-oncology
KW - Organs at risk
KW - Particle therapy
KW - European Particle Therapy Network
KW - INTENSITY-MODULATED RADIOTHERAPY
KW - RADIATION ONCOLOGISTS GUIDE
KW - WHOLE-BRAIN RADIOTHERAPY
KW - NASOPHARYNGEAL CARCINOMA
KW - NECK-CANCER
KW - NEUROCOGNITIVE FUNCTION
KW - CRANIAL IRRADIATION
KW - PROTON THERAPY
KW - HEARING-LOSS
KW - HEAD
U2 - 10.1016/j.radonc.2017.12.013
DO - 10.1016/j.radonc.2017.12.013
M3 - Article
SN - 0167-8140
VL - 128
SP - 37
EP - 43
JO - Radiotherapy and Oncology
JF - Radiotherapy and Oncology
IS - 1
ER -