TY - JOUR
T1 - The European baseline series in 10 European Countries, 2005/2006
T2 - Results of the European Surveillance System on Contact Allergies (ESSCA)
AU - Uter, Wolfgang
AU - Rämsch, Christiane
AU - Aberer, Werner
AU - Ayala, Fabio
AU - Balato, Anna
AU - Beliauskiene, Aiste
AU - Fortina, Anna Belloni
AU - Bircher, Andreas
AU - Brasch, Jochen
AU - Chowdhury, Mahbub M U
AU - Coenraads, Pieter Jan
AU - Schuttelaar, Marie-Louise
AU - Cooper, Sue
AU - Corradin, Maria Teresa
AU - Elsner, Peter
AU - English, John S C
AU - Fartasch, Manigè
AU - Mahler, Vera
AU - Frosch, Peter J
AU - Fuchs, Thomas
AU - Gawkrodger, David J
AU - Gimènez-Arnau, Ana-Maria
AU - Green, Cathy M
AU - Horne, Helen L
AU - Jolanki, Riitta
AU - King, Codagh M
AU - Krêcisz, Beata
AU - Kiec-Swierczynska, Marta
AU - Ormerod, Anthony D
AU - Orton, David I
AU - Peserico, Andrea
AU - Rantanen, Tapio
AU - Rustemeyer, Thomas
AU - Sansom, Jane E
AU - Simon, Dagmar
AU - Statham, Barry N
AU - Wilkinson, Mark
AU - Schnuch, Axel
PY - 2009/7
Y1 - 2009/7
N2 - BACKGROUND: Continual surveillance based on patch test results has proved useful for the identification of contact allergy.OBJECTIVES: To provide a current view on the spectrum of contact allergy to important sensitizers across Europe.PATIENTS/METHODS: Clinical and patch test data of 19 793 patients patch tested in 2005/2006 in the 31 participating departments from 10 European countries (the European Surveillance System on Contact Allergies' (ESSCA) www.essca-dc.org) were descriptively analysed, aggregated to four European regions.RESULTS: Nickel sulfate remains the most common allergen with standardized prevalences ranging from 19.7% (central Europe) to 24.4% (southern Europe). While a number of allergens shows limited variation across the four regions, such as Myroxylon pereirae (5.3-6.8%), cobalt chloride (6.2-8.8%) or thiuram mix (1.7-2.4%), the differences observed with other allergens may hint on underlying differences in exposures, for example: dichromate 2.4% in the UK (west) versus 4.5-5.9% in the remaining EU regions, methylchloroisothiazolinone/methylisothiazolinone 4.1% in the South versus 2.1-2.7% in the remaining regions.CONCLUSIONS: Notwithstanding residual methodological variation (affecting at least some 'difficult' allergens) tackled by ongoing efforts for standardization, a comparative analysis as presented provides (i) a broad overview on contact allergy frequencies and (ii) interesting starting points for further, in-depth investigation.
AB - BACKGROUND: Continual surveillance based on patch test results has proved useful for the identification of contact allergy.OBJECTIVES: To provide a current view on the spectrum of contact allergy to important sensitizers across Europe.PATIENTS/METHODS: Clinical and patch test data of 19 793 patients patch tested in 2005/2006 in the 31 participating departments from 10 European countries (the European Surveillance System on Contact Allergies' (ESSCA) www.essca-dc.org) were descriptively analysed, aggregated to four European regions.RESULTS: Nickel sulfate remains the most common allergen with standardized prevalences ranging from 19.7% (central Europe) to 24.4% (southern Europe). While a number of allergens shows limited variation across the four regions, such as Myroxylon pereirae (5.3-6.8%), cobalt chloride (6.2-8.8%) or thiuram mix (1.7-2.4%), the differences observed with other allergens may hint on underlying differences in exposures, for example: dichromate 2.4% in the UK (west) versus 4.5-5.9% in the remaining EU regions, methylchloroisothiazolinone/methylisothiazolinone 4.1% in the South versus 2.1-2.7% in the remaining regions.CONCLUSIONS: Notwithstanding residual methodological variation (affecting at least some 'difficult' allergens) tackled by ongoing efforts for standardization, a comparative analysis as presented provides (i) a broad overview on contact allergy frequencies and (ii) interesting starting points for further, in-depth investigation.
KW - clinical epidemiology
KW - contact allergy
KW - patch testing
KW - PATCH TEST SERIES
KW - MULTIFACTORIAL ANALYSIS
KW - METHYLDIBROMO GLUTARONITRILE
KW - TIXOCORTOL PIVALATE
KW - STANDARD SERIES
KW - RECOMMENDATION
KW - MULTICENTER
KW - FREQUENCY
KW - AGE
U2 - 10.1111/j.1600-0536.2009.01572.x
DO - 10.1111/j.1600-0536.2009.01572.x
M3 - Article
C2 - 19659962
SN - 0105-1873
VL - 61
SP - 31
EP - 38
JO - Contact Dermatitis
JF - Contact Dermatitis
IS - 1
ER -