TY - JOUR
T1 - The global burden of fracture-related infection
T2 - can we do better?
AU - Metsemakers, Willem Jan
AU - Moriarty, T. Fintan
AU - Morgenstern, Mario
AU - Marais, Leonard
AU - Onsea, Jolien
AU - O'Toole, Robert V.
AU - Depypere, Melissa
AU - Obremskey, William T.
AU - Verhofstad, Michael H.J.
AU - McNally, Martin
AU - Morshed, Saam
AU - Wouthuyzen-Bakker, Marjan
AU - Zalavras, Charalampos
N1 - Publisher Copyright:
© 2023 Elsevier Ltd
PY - 2024/6
Y1 - 2024/6
N2 - Fracture-related infection is a major complication related to musculoskeletal injuries that not only has important clinical consequences, but also a substantial socioeconomic impact. Although fracture-related infection is one of the oldest disease entities known to mankind, it has only recently been defined and, therefore, its global burden is still largely unknown. In this Personal View, we describe the origin of the term fracture-related infection, present the available data on its global impact, and discuss important aspects regarding its prevention and management that could lead to improved outcomes in both high-resource and low-resource settings. We also highlight the need for health-care systems to be adequately compensated for the high cost of human resources (trained staff) and well-equipped facilities required to adequately care for these complex patients. Our aim is to increase awareness among clinicians and policy makers that fracture-related infection is a disease entity that deserves prioritisation in terms of research, with the goal to standardise treatment and improve patient outcomes on a global scale.
AB - Fracture-related infection is a major complication related to musculoskeletal injuries that not only has important clinical consequences, but also a substantial socioeconomic impact. Although fracture-related infection is one of the oldest disease entities known to mankind, it has only recently been defined and, therefore, its global burden is still largely unknown. In this Personal View, we describe the origin of the term fracture-related infection, present the available data on its global impact, and discuss important aspects regarding its prevention and management that could lead to improved outcomes in both high-resource and low-resource settings. We also highlight the need for health-care systems to be adequately compensated for the high cost of human resources (trained staff) and well-equipped facilities required to adequately care for these complex patients. Our aim is to increase awareness among clinicians and policy makers that fracture-related infection is a disease entity that deserves prioritisation in terms of research, with the goal to standardise treatment and improve patient outcomes on a global scale.
UR - http://www.scopus.com/inward/record.url?scp=85178142459&partnerID=8YFLogxK
U2 - 10.1016/S1473-3099(23)00503-0
DO - 10.1016/S1473-3099(23)00503-0
M3 - Review article
AN - SCOPUS:85178142459
SN - 1473-3099
VL - 24
SP - e386-e393
JO - The Lancet Infectious Diseases
JF - The Lancet Infectious Diseases
IS - 6
ER -