The importance of left ventricular function for long-term outcome after primary percutaneous coronary intervention

Pieter A. van der Vleuten*, Saman Rasoul, Willem Huurnink, Iwan C. C. van der Horst, Riemer H. J. A. Slart, Stoffer Reiffers, Rudi A. Dierckx, Rene A. Tio, Jan Paul Ottervanger, Menko-Jan De Boer, Felix Zijlstra

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Background: In the present study we sought to determine the long-term prognostic value of left ventricular ejection fraction (LVEF), assessed by planar radionuclide ventriculography (PRV), after ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PPCI).

Methods: In total 925 patients underwent PRV for LVEF assessment after PPCI for myocardial infarction before discharge from the hospital. PRV was performed with a standard dose of 500 Mbq of Tc-99m-pertechnetate. Average follow-up time was 2.5 years.

Results: Mean (+/- SD) age was 60 +/- 12 years. Mean (+/- SD) LVEF was 45.7 +/- 12.2 %. 1 year survival was 97.3 % and 3 year survival was 94.2 %. Killip class, multi vessel-disease, previous cardiovascular events, peak creatin kinase and its MB fraction, age and LVEF proved to be univariate predictors of mortality. When entered in a forward conditional Cox regression model age and LVEF were independent predictors of 1 and 3 year mortality.

Conclusion: LVEF assessed by PRV is a powerful independent predictor of long term mortality after PPCI for STEMI.

Original languageEnglish
Article number4
Number of pages7
JournalBmc cardiovascular disorders
Volume8
DOIs
Publication statusPublished - 23-Feb-2008

Keywords

  • ACUTE MYOCARDIAL-INFARCTION
  • INSULIN-POTASSIUM INFUSION
  • EJECTION FRACTION
  • THROMBOLYTIC THERAPY
  • PRIMARY ANGIOPLASTY
  • CARDIAC-FUNCTION
  • MORTALITY
  • ECHOCARDIOGRAPHY
  • TRIAL
  • SURVIVORS

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