The importance of pre-treatment haemoglobin level in inoperable non-small cell lung carcinoma treated with radical radiotherapy

H Langendijk*, J de Jong, R Wanders, P Lambin, B Slotman

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

25 Citations (Scopus)

Abstract

Background and purpose: The purpose of this study was to evaluate the prognostic significance of the pre-treatment haemoglobin level among patients with inoperable non-small cell lung carcinorna (NSCLC) treated with definitive radiotherapy with regard to loco-regional tumour control (LC) and overall survival (OS).

Material and methods: Patients (n = 526) with previously untreated NSCLC, stages I-IIIb, WHO-performance status of 0-2 were eligible. All patients were treated with definitive external irradiation (60 Gy in 6 weeks).

Results: In the niultivariate analysis, the pre-treatment haemoglobin level was an independent prognostic factor for both loco-regional control and the overall survival.

Conclusions: pre-treatment haemoglobin levels are strongly associated with loco-regional tumour control and the overall survival. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)321-325
Number of pages5
JournalRadiotherapy and Oncology
Volume67
Issue number3
DOIs
Publication statusPublished - Jun-2003

Keywords

  • pre-treatment haemoglobin level
  • non-small cell lung carcinoma
  • radical radiotherapy
  • RADIATION-THERAPY
  • LOCAL-CONTROL
  • OXYGENATION PREDICTS
  • PROGNOSTIC-FACTORS
  • TUMOR OXYGENATION
  • UTERINE CERVIX
  • CANCER
  • SURVIVAL
  • ANEMIA
  • LARYNX

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