The influence of tumor necrosis factor-alpha and interleukin-10 gene promoter polymorphism on the inflammatory response in experimental human endotoxemia

J W Fijen; J E Tulleken; B G Hepkema; T S van der Werf; J J Ligtenberg; J G Zijlstra

doi:10.1086/323197

The influence of tumor necrosis factor-alpha and interleukin-10 gene promoter polymorphism on the inflammatory response in experimental human endotoxemia

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Abstract

In this study, we show that there is no correlation between tumor necrosis factor-alpha gene promoter polymorphism at position -308, interleukin-10 gene promoter polymorphism at position -1082, and the cytokine levels they produce in the human endotoxemia model.

Original language	English
Pages (from-to)	1601-1603
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	33
Issue number	9
DOIs	https://doi.org/10.1086/323197
Publication status	Published - 1-Nov-2001

Keywords

ANTIINFLAMMATORY CYTOKINE PROFILE
MENINGOCOCCAL DISEASE
BOWEL-DISEASE
MORTALITY
SEPSIS

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title = "The influence of tumor necrosis factor-alpha and interleukin-10 gene promoter polymorphism on the inflammatory response in experimental human endotoxemia",

abstract = "In this study, we show that there is no correlation between tumor necrosis factor-alpha gene promoter polymorphism at position -308, interleukin-10 gene promoter polymorphism at position -1082, and the cytokine levels they produce in the human endotoxemia model.",

keywords = "ANTIINFLAMMATORY CYTOKINE PROFILE, MENINGOCOCCAL DISEASE, BOWEL-DISEASE, MORTALITY, SEPSIS",

author = "Fijen, \{J W\} and Tulleken, \{J E\} and Hepkema, \{B G\} and \{van der Werf\}, \{T S\} and Ligtenberg, \{J J\} and Zijlstra, \{J G\}",

year = "2001",

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doi = "10.1086/323197",

language = "English",

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journal = "Clinical Infectious Diseases",

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T1 - The influence of tumor necrosis factor-alpha and interleukin-10 gene promoter polymorphism on the inflammatory response in experimental human endotoxemia

AU - Fijen, J W

AU - Tulleken, J E

AU - Hepkema, B G

AU - van der Werf, T S

AU - Ligtenberg, J J

AU - Zijlstra, J G

PY - 2001/11/1

Y1 - 2001/11/1

N2 - In this study, we show that there is no correlation between tumor necrosis factor-alpha gene promoter polymorphism at position -308, interleukin-10 gene promoter polymorphism at position -1082, and the cytokine levels they produce in the human endotoxemia model.

AB - In this study, we show that there is no correlation between tumor necrosis factor-alpha gene promoter polymorphism at position -308, interleukin-10 gene promoter polymorphism at position -1082, and the cytokine levels they produce in the human endotoxemia model.

KW - ANTIINFLAMMATORY CYTOKINE PROFILE

KW - MENINGOCOCCAL DISEASE

KW - BOWEL-DISEASE

KW - MORTALITY

KW - SEPSIS

U2 - 10.1086/323197

DO - 10.1086/323197

M3 - Article

C2 - 11588702

SN - 1058-4838

VL - 33

SP - 1601

EP - 1603

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 9

ER -

The influence of tumor necrosis factor-alpha and interleukin-10 gene promoter polymorphism on the inflammatory response in experimental human endotoxemia

Abstract

Keywords

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