The net effect of ANCA on neutrophil extracellular trap formation

Peter Heeringa, Abraham Rutgers, Cees G M Kallenberg

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)


The formation of neutrophil extracellular traps induced by antineutrophil cytoplasmic autoantibodies has been implicated in the pathogenesis of antineutrophil cytoplasmic autoantibody-associated vasculitis. Kraaij et al. now provide evidence that excessive neutrophil extracellular trap formation in vitro induced by sera from patients with antineutrophil cytoplasmic autoantibody-associated vasculitis is associated with active disease but is not dependent on the presence of antineutrophil cytoplasmic autoantibodies.

Original languageEnglish
Pages (from-to)14-16
Number of pages3
JournalKidney International
Issue number1
Publication statusPublished - Jul-2018

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