No separation is needed! The enantiomeric excess of unprotected amino acids can be determined very reliable by P-31 NMR spectroscopy after derivatization as phosphonic amides 1. This rapid and simple analytical procedure, suitable for aqueous solutions. is also applicable for amino acid derivatives, chiral amines, and alcohols.
|Number of pages||2|
|Journal||Angewandte Chemie-International Edition in English|
|Publication status||Published - Aug-1992|
- GAS-CHROMATOGRAPHIC SEPARATION
- CHIRAL AUXILIARY COMPOUNDS
- NMR METHOD