The persistence of depression score

  • J. Spijker*
  • , R. de Graaf
  • , J. Ormel
  • , W. A. Nolen
  • , D. E. Grobbee
  • , H. Burger
  • *Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)
374 Downloads (Pure)

Abstract

Objective: To construct a score that allows prediction of major depressive episode (MDE) persistence in individuals with MDE using determinants of persistence identified in previous research.

Method: Data were derived from 250 subjects from the general population with new MDE according to DSM-III-R. These subjects were recruited from the Netherlands Mental Health Survey and Incidence Study (NEMESIS), using the Composite International Diagnostic Interview. Determinants for persistence were transformed into a practical risk score using proportional hazards models and bootstrapping techniques.

Results: The risk of MDE persistence after 12 months was 23%. The score comprised measures of physical illness, social support, depression severity and recurrency, and duration of previous episodes. With increasing categories of these measures, the predicted risks increased from 7 to 40%.

Conclusion: We constructed the Persistence of Depression Score (PDS) showing reasonable performance. The PDS could be of importance in clinical practice to support treatment decisions.

Original languageEnglish
Pages (from-to)411-416
Number of pages6
JournalActa Psychiatrica Scandinavica
Volume114
Issue number6
DOIs
Publication statusPublished - Dec-2006

Keywords

  • depression
  • prognosis
  • risk assessment
  • general population
  • MENTAL-HEALTH SURVEY
  • GENERAL-POPULATION
  • MAJOR DEPRESSION
  • PRIMARY-CARE
  • NEMESIS
  • EPISODES
  • PSYCHOPATHOLOGY
  • DISABILITY
  • DISORDERS
  • INTERVIEW

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