The pharmacokinetic and biological activity profile of dexamethasone targeted to sinusoidal endothelial and Kupffer cells

B.N Melgert, B Weert, H Schellekens, D.K F Meijer, Klaas Poelstra

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)
Original languageEnglish
Pages (from-to)1 - 10
Number of pages10
JournalJournal of Drug Targeting
Volume11
Issue number1
DOIs
Publication statusPublished - Jan-2003

Keywords

  • liver fibrosis
  • cirrhosis
  • dexamethasone
  • drug targeting
  • human serum albumin
  • neoglycoproteins
  • HEPATIC STELLATE CELLS
  • BILE-DUCT LIGATION
  • LIVER FIBROSIS
  • TNF-ALPHA
  • EXPRESSION
  • RAT
  • ALBUMIN
  • GLUCOCORTICOIDS
  • INHIBITION
  • ACTIVATION

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