The recolonization hypothesis in a full-mouth or multiple-session treatment protocol: a blinded, randomized clinical trial

Vincent Zijnge, Henriette F. Meijer, Mady-Ann Lie, Jan A. H. Tromp, John E. Degener, Hermie J. M. Harmsen, Frank Abbas*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

P>Aim

To test recolonization of periodontal lesions after full-mouth scaling and root planing (FM-SRP) or multiple session-SRP (MS-SRP) in a randomized clinical trial and whether FM-SRP and MS-SRP result in different clinical outcomes.

Materials and Methods

Thirty-nine subjects were randomly assigned to FM-SRP or MS-SRP groups. At baseline and after 3 months, probing pocket depth (PPD), plaque index (PlI) and bleeding on probing (BoP) were recorded. At baseline, immediately after treatment, after 1, 2, 7, 14 and 90 days, paper point samples from a single site from the maxillary right quadrant were collected for microbiological analysis of five putative pathogens by polymerase chain reaction.

Results

FM-SRP and MS-SRP resulted in significant reductions in PPD, BoP and PlI and the overall detection frequencies of the five species after 3 months without significant differences between treatments. Compared with MS-SRP, FM-SRP resulted in less recolonization of the five species, significantly for Treponema denticola, in the tested sites.

Conclusion

FM-SRP and MS-SRP result in overall clinically and microbiologically comparable outcomes where recolonization of periodontal lesions may be better prevented by FM-SRP.

Original languageEnglish
Pages (from-to)518-525
Number of pages8
JournalJournal of Clinical Periodontology
Volume37
Issue number6
DOIs
Publication statusPublished - Jun-2010

Keywords

  • bacteria
  • full-mouth-SRP
  • multiple session SRP
  • periodontitis
  • polymerase chain reaction
  • recolonization
  • NONSURGICAL PERIODONTAL THERAPY
  • 5TH EUROPEAN WORKSHOP
  • MICROBIOLOGICAL OBSERVATIONS
  • ULTRASONIC DEBRIDEMENT
  • CONSENSUS REPORT
  • SUBGINGIVAL MICROFLORA
  • IMMUNE-RESPONSE
  • PROBING FORCE
  • QUADRANT
  • DISINFECTION

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