The role of fitness in the association between fatness and cardiometabolic risk from childhood to adolescence

Silvia I. Brouwer*, Ronald P. Stolk, Eryn T. Liem, Koen A. P. M. Lemmink, Eva Corpeleijn

*Corresponding author for this work

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Abstract

Background Fatness and fitness both influence cardiometabolic risk. Objective The purpose of this study was to investigate whether childhood fatness and increasing fatness from childhood to adolescence are associated with cardiometabolic risk during adolescence and how fitness affects this association. Subjects and methods Of 565 adolescents (283 boys and 282 girls) from the TRacking Adolescents Individual Life Survey (TRAILS) data on anthropometric parameters (age 11 and 16), metabolic parameters, and fitness (age 16) were available. Body mass index and skinfolds were used as measures for fatness. Increasing fatness was calculated by subtracting Z-scores for fatness at age 11 from Z-score fatness at age 16. Cardiometabolic risk was calculated as the average of the standardized means of mean arterial pressure, fasting serum triglycerides, high-density lipoprotein-cholesterol, glucose, and waist circumference. Insulin resistance was calculated by homeostasis model assessment-insulin resistance (HOMA-IR). Fitness was estimated as maximal oxygen consumption (VO2max) during a shuttle run test. Results Boys showed a higher clustered cardiometabolic risk when compared to girls (p?

Original languageEnglish
Pages (from-to)57-65
Number of pages9
JournalPediatric Diabetes
Volume14
Issue number1
DOIs
Publication statusPublished - Feb-2013

Keywords

  • body mass index
  • insulin resistance
  • metabolic syndrome
  • physical fitness
  • skinfold thickness
  • BODY-MASS INDEX
  • CARDIORESPIRATORY FITNESS
  • METABOLIC SYNDROME
  • PHYSICAL-ACTIVITY
  • DISEASE RISK
  • INSULIN-RESISTANCE
  • PUBERTAL CHANGES
  • YOUNG ADULTHOOD
  • AEROBIC FITNESS
  • CHILDREN

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