The role of itraconazole in preventing and treating systemic fungal infections in immunocompromised patients

M Potter*, JP Donnelly

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Abstract

The increasing use of immunosuppressive chemotherapy and allogeneic transplants for haematological malignancies has increased the number of patients at risk of systemic fungal infections (SFIs). A number of antifungal agents are now available. This paper reports the deliberations of an expert panel that considered the role of itraconazole. It concluded that itraconazole has an important role in the prophylaxis and treatment of SFIs whether proven or not. Copyright (C) 2004 S. Karger AG, Basel.

Original languageEnglish
Pages (from-to)175-180
Number of pages6
JournalACTA HAEMATOLOGICA
Volume111
Issue number3
DOIs
Publication statusPublished - 2004

Keywords

  • fungal infection, systemic
  • itraconazole
  • malignancy, haematological
  • neutropenia
  • EMPIRICAL ANTIFUNGAL THERAPY
  • BONE-MARROW-TRANSPLANTATION
  • NEUTROPENIC PATIENTS
  • AMPHOTERICIN-B
  • ORAL SOLUTION
  • DOUBLE-BLIND
  • INVASIVE ASPERGILLOSIS
  • MULTICENTER TRIAL
  • PERSISTENT FEVER
  • PROPHYLAXIS

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