@inproceedings{fc99ef29aaae4e0c8129d56a8a0ba5e4,
title = "The role of long-chain polyunsaturated fatty acids (LCPUFA) in growth and development",
abstract = "It is debatable whether supplementation of infant formula with LCPUFA has an effect on infant growth and development. Up till now, there is little evidence of a negative effect on infant growth. A review of randomized controlled trials in term infants revealed that LCPUFA, in particularly supplementation with >= 0.30% DHA, seems to have a beneficial effect on neurodevelopmental outcome up to 4 months of age. The studies could not demonstrate a consistent positive effect beyond that age. However, in the majority of studies neurodevelopmental outcome was assessed between 6 to 24 months, i.e. at an age where there is a 'latency' in the expression of minor neurological dysfunction. Thus it is possible that LCPUFA might have a long lasting beneficial effect on neurodevelopmental outcome at school-age and beyond. This hypothesis urgently needs testing.",
keywords = "LCPUFA, DHA, AA, growth, neurodevelopmental outcome, visual development, general movements, HEALTHY TERM INFANTS, GENERAL MOVEMENTS, CONTROLLED-TRIAL, VISUAL-ACUITY, SUPPLEMENTATION, QUOTIENT, FORMULA, MILK, ESSENTIALITY, QUALITY",
author = "M Hadders-Algra",
year = "2005",
language = "English",
isbn = "*************",
series = "ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY",
publisher = "Springer",
pages = "80--94",
editor = "B Koletzko and P Dodds and H Akerblom and M Ashwell",
booktitle = "EARLY NUTRITION AND ITS LATER CONSEQUENCES: NEW OPPORTUNITIES",
note = "Conference on Early Nutrition and Its Later Consequences ; Conference date: 02-07-2004 Through 03-07-2004",
}