The small heat shock proteins family: The long forgotten chaperones

C. Garrido; C. Paul; R. Seigneuric; H. H. Kampinga

doi:10.1016/j.biocel.2012.02.022

The small heat shock proteins family: The long forgotten chaperones

C. Garrido^*, C. Paul, R. Seigneuric, H. H. Kampinga

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

194 Citations (Scopus)

Abstract

Small heat shock proteins are a rather heterogeneous family of ATP-independent chaperones, some of which have been proven to block protein aggregation and help the cells to survive stressful conditions. Although much less studied than high molecular weight HSPs like HSP70/HSPA or HSP90/HSPC, their implication in physio-pathological processes and human diseases is now well evidenced, as it will be discussed in the different reviews of this special issue. In this mini-review we will just present a general introduction about the small heat shock proteins family. This article is part of a Directed Issue entitled: Small HSPs in physiology and pathology. (C) 2012 Published by Elsevier Ltd.

Original language	English
Pages (from-to)	1588-1592
Number of pages	5
Journal	International journal of biochemistry & cell biology
Volume	44
Issue number	10
DOIs	https://doi.org/10.1016/j.biocel.2012.02.022
Publication status	Published - Oct-2012

Keywords

Small Heat Shock Protein
Chaperone
Chaperonopathies
HSPB
ALPHA-B-CRYSTALLIN
A-CRYSTALLIN
METHYLGLYOXAL MODIFICATION
HSP27 OLIGOMERIZATION
OXIDATIVE STRESS
CYTOCHROME-C
CELL-DEATH
IN-VITRO
PHOSPHORYLATION
HEAT-SHOCK-PROTEIN-27

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title = "The small heat shock proteins family: The long forgotten chaperones",

abstract = "Small heat shock proteins are a rather heterogeneous family of ATP-independent chaperones, some of which have been proven to block protein aggregation and help the cells to survive stressful conditions. Although much less studied than high molecular weight HSPs like HSP70/HSPA or HSP90/HSPC, their implication in physio-pathological processes and human diseases is now well evidenced, as it will be discussed in the different reviews of this special issue. In this mini-review we will just present a general introduction about the small heat shock proteins family. This article is part of a Directed Issue entitled: Small HSPs in physiology and pathology. (C) 2012 Published by Elsevier Ltd.",

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author = "C. Garrido and C. Paul and R. Seigneuric and Kampinga, {H. H.}",

year = "2012",

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language = "English",

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T2 - The long forgotten chaperones

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AU - Paul, C.

AU - Seigneuric, R.

AU - Kampinga, H. H.

PY - 2012/10

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KW - Chaperonopathies

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KW - ALPHA-B-CRYSTALLIN

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KW - METHYLGLYOXAL MODIFICATION

KW - HSP27 OLIGOMERIZATION

KW - OXIDATIVE STRESS

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KW - CELL-DEATH

KW - IN-VITRO

KW - PHOSPHORYLATION

KW - HEAT-SHOCK-PROTEIN-27

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DO - 10.1016/j.biocel.2012.02.022

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EP - 1592

JO - International journal of biochemistry & cell biology

JF - International journal of biochemistry & cell biology

IS - 10

ER -

The small heat shock proteins family: The long forgotten chaperones

Abstract

Keywords

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