The Timing of Sleep in Depression: Theoretical Considerations

Domien G.M. Beersma, Serge Daan, Rutger H. van den Hoofdakker

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13 Citations (Scopus)


Endogenously depressed subjects frequently show severe sleep problems. In this article sleep time in depression is discussed in relation to a recently developed model for sleep timing in healthy subjects. In terms of the model, two parameter sets survive a qualitative comparison with the empirical data. These are a deficient increase of sleep need (process S) and, alternatively, an increased amplitude of random fluctuations in the wake threshold (process C). Distinct predictions based on these alternatives are discussed.
Original languageEnglish
Pages (from-to)253-262
Number of pages10
JournalPsychiatry Research
Issue number3
Publication statusPublished - 1985


  • simulations
  • EEG power
  • sleep timing
  • sleep-wake rhythm
  • endogenous depression

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