Thermochemiluminescence and its application in immunoassay

Adamantylideneadamantane 1,2-dioxetane (1) is a 1,2-dioxetane with a half-life of about 16,000 years at room temperature. The half-life of 1 decreases exponentially at higher temperatures and is only 25 seconds at 240"C. Blue light is emitted during the decomposition of tho fourmembered 1,2-dioxetane ring of 1. The photons, which are emitted during the chemical reaction can be counted by a sophisticated photon counter. This photon counter can distinguish an amount of 3*10-13 gram of 1 (10-15 mole) from the background luminescence. ... Zie: Summary