Thermoresponsive hydrogels based on poly (N-isopropylacrylamide)/chondroitin sulfate

Justin M.  Varghese; Yahya A. Ismail; Chang Kee Lee; Kwang Min Shin; Min Kyoon Shin; Sun I. Kim; Insuk So; Seon Jeong Kim

doi:10.1016/j.snb.2008.09.001

Thermoresponsive hydrogels based on poly (N-isopropylacrylamide)/chondroitin sulfate

Justin M. Varghese
, Yahya A. Ismail
, Chang Kee Lee
, Kwang Min Shin
, Min Kyoon Shin
, Sun I. Kim
, Insuk So
, Seon Jeong Kim

Research output: Contribution to journal › Article › Academic › peer-review

37 Citations (Scopus)

Abstract

A fast, thermoresponsive hydrogel composed of poly(N-isopropylacrylamide) (PNIPAm) and chondroitin sulfate (ChS) was synthesized using precipitation polymerization. ChS was introduced to increase the water absorption of the PNIPAm hydrogel, and the precipitation polymerization method was used to induce a porous network morphology to enhance the thermal response of the hydrogel. PNIPAm/ChS hydrogels (15:7.5 wt.%) underwent a very fast deswelling, within a period of approximately 2 min, due to the presence of a large free water content (∼90–94%), which was associated with the interconnected filamentous morphology within the hydrogel. The swelling ratio was greatly enhanced by the addition of ChS. The hydrogels exhibited stable thermoactuation behavior, following a volume change of 75% while cycling the temperature between 20 and 45 °C.

Original language	English
Pages (from-to)	336-341
Number of pages	6
Journal	Sensors and Actuators B: Chemical
Volume	135
Issue number	1
DOIs	https://doi.org/10.1016/j.snb.2008.09.001
Publication status	Published - 10-Dec-2008
Externally published	Yes

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Thermoresponsive hydrogels based on poly (N-isopropylacrylamide)
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title = "Thermoresponsive hydrogels based on poly (N-isopropylacrylamide)/chondroitin sulfate",

abstract = "A fast, thermoresponsive hydrogel composed of poly(N-isopropylacrylamide) (PNIPAm) and chondroitin sulfate (ChS) was synthesized using precipitation polymerization. ChS was introduced to increase the water absorption of the PNIPAm hydrogel, and the precipitation polymerization method was used to induce a porous network morphology to enhance the thermal response of the hydrogel. PNIPAm/ChS hydrogels (15:7.5 wt.\%) underwent a very fast deswelling, within a period of approximately 2 min, due to the presence of a large free water content (∼90–94\%), which was associated with the interconnected filamentous morphology within the hydrogel. The swelling ratio was greatly enhanced by the addition of ChS. The hydrogels exhibited stable thermoactuation behavior, following a volume change of 75\% while cycling the temperature between 20 and 45 °C.",

author = "Varghese, \{Justin M.\} and Ismail, \{Yahya A.\} and Lee, \{Chang Kee\} and Shin, \{Kwang Min\} and Shin, \{Min Kyoon\} and Kim, \{Sun I.\} and Insuk So and Kim, \{Seon Jeong\}",

year = "2008",

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day = "10",

doi = "10.1016/j.snb.2008.09.001",

language = "English",

volume = "135",

pages = "336--341",

journal = "Sensors and Actuators B: Chemical",

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TY - JOUR

T1 - Thermoresponsive hydrogels based on poly (N-isopropylacrylamide)/chondroitin sulfate

AU - Varghese, Justin M.

AU - Ismail, Yahya A.

AU - Lee, Chang Kee

AU - Shin, Kwang Min

AU - Shin, Min Kyoon

AU - Kim, Sun I.

AU - So, Insuk

AU - Kim, Seon Jeong

PY - 2008/12/10

Y1 - 2008/12/10

N2 - A fast, thermoresponsive hydrogel composed of poly(N-isopropylacrylamide) (PNIPAm) and chondroitin sulfate (ChS) was synthesized using precipitation polymerization. ChS was introduced to increase the water absorption of the PNIPAm hydrogel, and the precipitation polymerization method was used to induce a porous network morphology to enhance the thermal response of the hydrogel. PNIPAm/ChS hydrogels (15:7.5 wt.%) underwent a very fast deswelling, within a period of approximately 2 min, due to the presence of a large free water content (∼90–94%), which was associated with the interconnected filamentous morphology within the hydrogel. The swelling ratio was greatly enhanced by the addition of ChS. The hydrogels exhibited stable thermoactuation behavior, following a volume change of 75% while cycling the temperature between 20 and 45 °C.

AB - A fast, thermoresponsive hydrogel composed of poly(N-isopropylacrylamide) (PNIPAm) and chondroitin sulfate (ChS) was synthesized using precipitation polymerization. ChS was introduced to increase the water absorption of the PNIPAm hydrogel, and the precipitation polymerization method was used to induce a porous network morphology to enhance the thermal response of the hydrogel. PNIPAm/ChS hydrogels (15:7.5 wt.%) underwent a very fast deswelling, within a period of approximately 2 min, due to the presence of a large free water content (∼90–94%), which was associated with the interconnected filamentous morphology within the hydrogel. The swelling ratio was greatly enhanced by the addition of ChS. The hydrogels exhibited stable thermoactuation behavior, following a volume change of 75% while cycling the temperature between 20 and 45 °C.

U2 - 10.1016/j.snb.2008.09.001

DO - 10.1016/j.snb.2008.09.001

M3 - Article

SN - 0925-4005

VL - 135

SP - 336

EP - 341

JO - Sensors and Actuators B: Chemical

JF - Sensors and Actuators B: Chemical

IS - 1

ER -

Thermoresponsive hydrogels based on poly (N-isopropylacrylamide)/chondroitin sulfate

Abstract

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