Abstract
Introduction: A prolonged incubation time is generally recommended for diagnosing periprosthetic joint infections (PJI). However, in literature, no distinction is made between acute and chronic infections.
Methods: All patients with a PJI that underwent surgical debridement between November 2015 and February 2019 with or without revision of the prosthesis were retrospectively evaluated. Synovial fluid, 5 intraoperative periprosthetic tissue samples, and the sonicated prosthesis were cultured.
Results: Fifty-nine patients were analyzed, including 21 acute PJIs (33 isolates) and 38 chronic PJIs (46 isolates). In acute PJIs, all isolates grew within 5 days, while this took 11 days for chronic PJIs. Sonication fluid showed the shortest time to positivity (78% at day 2) for chronic PJIs, but no difference was observed for acute PJIs compared to tissue cultures.
Conclusion: In contrast to cultures from chronic PJIs, acute PJIs do not need a prolonged incubation time and no clear benefit is observed for sonication. (C) 2020 The Authors. Published by Elsevier Inc.
Original language | English |
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Article number | 115178 |
Number of pages | 6 |
Journal | Diagnostic microbiology and infectious disease |
Volume | 99 |
Issue number | 1 |
Early online date | 14-Aug-2020 |
DOIs | |
Publication status | Published - Jan-2021 |
Keywords
- Periprosthetic joint infection
- Diagnosis
- Acute
- Chronic
- Time to positivity
- Sonication
- PROPIONIBACTERIUM-ACNES
- DIAGNOSIS
- BIOFILMS