Towards erythropoietin mimicking small molecules

Alexander Doemling*, Barbara Beck, William Baumbach, Gregor Larbig

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Abstract

Small molecules potentially mimicking the hormone erythropoietin have been discovered by screening of a library of rationally designed multicomponent reaction molecules in a functional cell-based assay. (c) 2006 Published by Elsevier Ltd.

Original languageEnglish
Pages (from-to)379-384
Number of pages6
JournalBioorganic & Medicinal Chemistry Letters
Volume17
Issue number2
DOIs
Publication statusPublished - 15-Jan-2007
Externally publishedYes

Keywords

  • IMCR
  • passerini
  • ugi
  • isocyanide
  • erythropoietin
  • design
  • combinatorial chemistry
  • ISCHEMIA-REPERFUSION INJURY
  • IN-VIVO
  • FUSION PROTEIN
  • RECEPTOR
  • ACTIVATION
  • DIMERIZATION
  • DISCOVERY
  • INHIBITOR
  • MECHANISM
  • MIMETICS

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