Towards erythropoietin mimicking small molecules

Alexander Doemling; Barbara Beck; William Baumbach; Gregor Larbig

doi:10.1016/j.bmcl.2006.10.040

Towards erythropoietin mimicking small molecules

Alexander Doemling^*, Barbara Beck, William Baumbach, Gregor Larbig

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

8 Citations (Scopus)

Abstract

Small molecules potentially mimicking the hormone erythropoietin have been discovered by screening of a library of rationally designed multicomponent reaction molecules in a functional cell-based assay. (c) 2006 Published by Elsevier Ltd.

Original language	English
Pages (from-to)	379-384
Number of pages	6
Journal	Bioorganic & Medicinal Chemistry Letters
Volume	17
Issue number	2
DOIs	https://doi.org/10.1016/j.bmcl.2006.10.040
Publication status	Published - 15-Jan-2007
Externally published	Yes

Keywords

IMCR
passerini
ugi
isocyanide
erythropoietin
design
combinatorial chemistry
ISCHEMIA-REPERFUSION INJURY
IN-VIVO
FUSION PROTEIN
RECEPTOR
ACTIVATION
DIMERIZATION
DISCOVERY
INHIBITOR
MECHANISM
MIMETICS

Access to Document

10.1016/j.bmcl.2006.10.040

Cite this

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title = "Towards erythropoietin mimicking small molecules",

abstract = "Small molecules potentially mimicking the hormone erythropoietin have been discovered by screening of a library of rationally designed multicomponent reaction molecules in a functional cell-based assay. (c) 2006 Published by Elsevier Ltd.",

keywords = "IMCR, passerini, ugi, isocyanide, erythropoietin, design, combinatorial chemistry, ISCHEMIA-REPERFUSION INJURY, IN-VIVO, FUSION PROTEIN, RECEPTOR, ACTIVATION, DIMERIZATION, DISCOVERY, INHIBITOR, MECHANISM, MIMETICS",

author = "Alexander Doemling and Barbara Beck and William Baumbach and Gregor Larbig",

year = "2007",

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day = "15",

doi = "10.1016/j.bmcl.2006.10.040",

language = "English",

volume = "17",

pages = "379--384",

journal = "Bioorganic & Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "American Chemical Society",

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T1 - Towards erythropoietin mimicking small molecules

AU - Doemling, Alexander

AU - Beck, Barbara

AU - Baumbach, William

AU - Larbig, Gregor

PY - 2007/1/15

Y1 - 2007/1/15

N2 - Small molecules potentially mimicking the hormone erythropoietin have been discovered by screening of a library of rationally designed multicomponent reaction molecules in a functional cell-based assay. (c) 2006 Published by Elsevier Ltd.

AB - Small molecules potentially mimicking the hormone erythropoietin have been discovered by screening of a library of rationally designed multicomponent reaction molecules in a functional cell-based assay. (c) 2006 Published by Elsevier Ltd.

KW - IMCR

KW - passerini

KW - ugi

KW - isocyanide

KW - erythropoietin

KW - design

KW - combinatorial chemistry

KW - ISCHEMIA-REPERFUSION INJURY

KW - IN-VIVO

KW - FUSION PROTEIN

KW - RECEPTOR

KW - ACTIVATION

KW - DIMERIZATION

KW - DISCOVERY

KW - INHIBITOR

KW - MECHANISM

KW - MIMETICS

U2 - 10.1016/j.bmcl.2006.10.040

DO - 10.1016/j.bmcl.2006.10.040

M3 - Article

VL - 17

SP - 379

EP - 384

JO - Bioorganic & Medicinal Chemistry Letters

JF - Bioorganic & Medicinal Chemistry Letters

SN - 0960-894X

IS - 2

ER -