Transition-Metal-Free Catalysts for the Sustainable Epoxidation of Alkenes: From Discovery to Optimisation by Means of High Throughput Experimentation

Warunee Lueangchaichaweng, Inge Geukens, Annelies Peeters, Benjamin Jarry, Franck Launay, Jean-Luc Bonardet, Pierre A. Jacobs, Paolo P. Pescarmona*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Abstract

Transition-metal-free oxides were studied as heterogeneous catalysts for the sustainable epoxidation of alkenes with aqueous H2O2 by means of high throughput experimentation (HTE) techniques. A full-factorial HTE approach was applied in the various stages of the development of the catalysts: the synthesis of the materials, their screening as heterogeneous catalysts in liquid-phase epoxidation and the optimisation of the reaction conditions. Initially, the chemical composition of transition-metal-free oxides was screened, leading to the discovery of gallium oxide as a novel, active and selective epoxidation catalyst. On the basis of these results, the research line was continued with the study of structured porous aluminosilicates, gallosilicates and silica-gallia composites. In general, the gallium-based materials showed the best catalytic performances. This family of materials represents a promising class of heterogeneous catalysts for the sustainable epoxidation of alkenes and offers a valid alternative to the transition-metal heterogeneous catalysts commonly used in epoxidation. High throughput experimentation played an important role in promoting the development of these catalytic systems.

Original languageEnglish
Pages (from-to)140-151
Number of pages12
JournalCombinatorial Chemistry & High Throughput Screening
Volume15
Issue number2
Publication statusPublished - Feb-2012
Externally publishedYes

Keywords

  • Gallium oxide
  • Al-SBA-15
  • Ga-SBA-15
  • sustainable epoxidation
  • full-factorial
  • MESOPOROUS MOLECULAR-SIEVES
  • HYDROGEN-PEROXIDE
  • HETEROGENEOUS CATALYSIS
  • TI-MCM-41 NANOPARTICLES
  • ALUMINA
  • COMBINATORIAL
  • OXIDATION
  • SBA-15
  • CHEMISTRY
  • SILICA

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